English Dictionary |
OXYGENASE
Pronunciation (US): | (GB): |
Dictionary entry overview: What does oxygenase mean?
• OXYGENASE (noun)
The noun OXYGENASE has 1 sense:
1. an oxidoreductase that catalyzes the incorporation of molecular oxygen
Familiarity information: OXYGENASE used as a noun is very rare.
Dictionary entry details
Sense 1
Meaning:
An oxidoreductase that catalyzes the incorporation of molecular oxygen
Classified under:
Nouns denoting substances
Hypernyms ("oxygenase" is a kind of...):
oxidoreductase (an enzyme that catalyzes oxidation-reduction)
Context examples
The cytochrome P450 (CYP450) mono-oxygenase family of enzymes catalyzes the majority of the phase I reactions.
(Phase I Enzymes Inhibitor, NCI Thesaurus)
Certain allelic variants of the HMOX1 gene are associated with heme oxygenase 1 deficiency.
(HMOX1 wt Allele, NCI Thesaurus)
The anti-inflammatory actions of IL-10 appear to require induction of the enzyme heme oxygenase-1 (HO-1) through a map kinase pathway involving the p38 kinases.
(IL10 Anti-inflammatory Signaling Pathway, NCI Thesaurus/BIOCARTA)
Heme oxygenase 1 (288 aa, ~33 kDa) is encoded by the human HMOX1 gene.
(Heme Oxygenase 1, NCI Thesaurus)
Unlike traditional nonselective NSAIDs, meloxicam preferentially inhibits the activity of cyclo-oxygenase II (COX-II), resulting in a decreased conversion of arachidonic acid into prostaglandin precursors.
(Meloxicam, NCI Thesaurus)
Celecoxib selectively inhibits cyclo-oxygenase-2 activity (COX-2); COX-2 inhibition may result in apoptosis and a reduction in tumor angiogenesis and metastasis.
(Celecoxib, NCI Thesaurus)
Naproxen inhibits the activity of the enzymes cyclo-oxygenase I and II, resulting in a decreased formation of precursors of prostaglandins and thromboxanes.
(Naproxen, NCI Thesaurus)
Ketoprofen inhibits the activity of the enzymes cyclo-oxygenase I and II, resulting in a decreased formation of precursors of prostaglandins and thromboxanes.
(Ketoprofen, NCI Thesaurus)
In addition, CAPE inhibits PDGF-induced proliferation of vascular smooth muscle cells through the activation of p38 mitogen-activated protein kinase (MAPK) and hypoxia-inducible factor (HIF)-1alpha and subsequent induction of heme oxygenase-1 (HO-1).
(Caffeic Acid Phenethyl Ester, NCI Thesaurus)
Cyclo-oxygenase inhibitors belong to the family of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs).
(Cyclooxygenase inhibitor, NCI Dictionary)
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