ORPHENADRINE

Pronunciation (US):

(GB):

 Dictionary entry overview: What does orphenadrine mean? 

• ORPHENADRINE (noun)
  The noun ORPHENADRINE has 1 sense:

1. a skeletal muscle relaxant (trade name Norflex) used to treat severe muscle strain and Parkinsonism

  Familiarity information: ORPHENADRINE used as a noun is very rare.

 Dictionary entry details 

• ORPHENADRINE (noun)

Sense 1

Meaning:

A skeletal muscle relaxant (trade name Norflex) used to treat severe muscle strain and Parkinsonism

Classified under:

Nouns denoting man-made objects

Synonyms:

Norflex; orphenadrine

Hypernyms ("orphenadrine" is a kind of...):

muscle relaxant (a drug that reduces muscle contractility by blocking the transmission of nerve impulses or by decreasing the excitability of the motor end plate or by other actions)

 Context examples 

Although the mechanism of action has not been determined, orphenadrine appears to block muscarinic acetylcholine receptors as well as N-methyl-D-aspartate (NMDA) receptors in the central nervous system (CNS).

(Orphenadrine, NCI Thesaurus)

Although the mechanism of action has not been fully elucidated, orphenadrine citrate appears to block cholinergic receptors, thereby interfering with the transmission of nerve impulses from the spinal cord to the muscles.

(Orphenadrine Citrate, NCI Thesaurus)

In addition, orphenadrine exerts antagonistic effects on histamine H1 receptors.

(Orphenadrine, NCI Thesaurus)

The citrate salt form of orphenadrine with a muscle relaxant property.

(Orphenadrine Citrate, NCI Thesaurus)