ONCE

Pronunciation (US):

(GB):

IPA (US):

 Dictionary entry overview: What does once mean? 

• ONCE (adverb)
  The adverb ONCE has 3 senses:

1. on one occasion

2. as soon as

3. at a previous time

  Familiarity information: ONCE used as an adverb is uncommon.

 Dictionary entry details 

• ONCE (adverb)

Sense 1

Meaning:

On one occasion

Synonyms:

in one case; once; one time

Context example:

once I ran into her

Sense 2

Meaning:

As soon as

Context example:

once we are home, we can rest

Sense 3

Meaning:

At a previous time

Synonyms:

at one time; erst; erstwhile; formerly; once

Context example:

she was a dancer once

 Context examples 

I will trouble you once again.

(The Return of Sherlock Holmes, by Sir Arthur Conan Doyle)

Once treatment has ended, the catheter and balloon are removed.

(Balloon Brachytherapy, NCI Dictionary)

The man, the human being, broke the spell at once.

(Jane Eyre, by Charlotte Brontë)

Once your doctor knows the cause and severity of the condition, he or she can create a treatment plan for you.

(Aplastic Anemia, NIH: National Heart, Lung, and Blood Institute)

Upon administration, catiogenic and fusiogenic lipids promote anti-PKN3 siRNA Atu02 uptake by tumor cells; the siRNAs moieties are subsequently released once inside the cell.

(Anti-PKN3 siRNA Atu027, NCI Thesaurus)

AJs may also function in the transmission of the contact inhibition' signal, which instructs cells to stop dividing once an epithelial sheet is complete.

(Beta Catenin, NCI Thesaurus/from OMIM)

Lucy seems more restful than she has been for some time, and fell asleep at once.

(Dracula, by Bram Stoker)

Once released, these fatty acids travel through the blood to other tissues such as muscle where they are oxidized to provide energy through the mitochondrial beta-oxidation pathway.

(Beta-Oxidation of Fatty Acids Pathway, NCI Thesaurus/BIOCARTA)

Once inside the neuron, the light chain is translocated across the vesicular membrane to act as a protease on cytoplasmic substrates.

(Botulin Pathway, NCI Thesaurus/BIOCARTA)

A once yearly checking for disease in the absence of symptoms.

(Annual Screening, NCI Thesaurus)