OMEPRAZOLE

Pronunciation (US):

(GB):

 Dictionary entry overview: What does omeprazole mean? 

• OMEPRAZOLE (noun)
  The noun OMEPRAZOLE has 1 sense:

1. antacid (trade name Prilosec) that suppresses acid secretion in the stomach

  Familiarity information: OMEPRAZOLE used as a noun is very rare.

 Dictionary entry details 

• OMEPRAZOLE (noun)

Sense 1

Meaning:

Antacid (trade name Prilosec) that suppresses acid secretion in the stomach

Classified under:

Nouns denoting substances

Synonyms:

omeprazole; Prilosec

Hypernyms ("omeprazole" is a kind of...):

alkaliser; alkalizer; antacid; antiacid; gastric antacid (an agent that counteracts or neutralizes acidity (especially in the stomach))

 Context examples 

The S-isomer of omeprazole, with gastric proton pump inhibitor activity.

(Esomeprazole, NCI Thesaurus)

The sodium salt of the S-isomer of omeprazole, with gastric proton pump inhibitor activity.

(Esomeprazole Sodium, NCI Thesaurus)

The magnesium salt of esomeprazole, the S-isomer of omeprazole, with gastric proton pump inhibitor activity.

(Esomeprazole magnesium, NCI Thesaurus)

A 4-ethylthio-3-methylpyridine analogue of omeprazole with no substituent on the benzimidazole ring, with selective and irreversible proton pump inhibitor activity.

(Disuprazole, NCI Thesaurus)

In the acidic compartment of parietal cells, omeprazole is protonated and converted into the active achiral sulfenamide; the active sulfenamide forms one or more covalent disulfide bonds with the proton pump hydrogen-potassium adenosine triphosphatase (H+/K+ ATPase), thereby inhibiting its activity and the parietal cell secretion of H+ ions into the gastric lumen, the final step in gastric acid production.

(Omeprazole Magnesium, NCI Thesaurus)

Omeprazole forms a stable disulfide bond with the sulfhydryl group of the hydrogen-potassium (H+ - K+) ATPase found on the secretory surface of parietal cells, thereby inhibiting the final transport of hydrogen ions (via exchange with potassium ions) into the gastric lumen and suppressing gastric acid secretion.

(Omeprazole, NCI Thesaurus)