NOTOCHORD

Pronunciation (US):

(GB):

IPA (US):

 Dictionary entry overview: What does notochord mean? 

• NOTOCHORD (noun)
  The noun NOTOCHORD has 1 sense:

1. a flexible rodlike structure that forms the supporting axis of the body in the lowest chordates and lowest vertebrates and in embryos of higher vertebrates

  Familiarity information: NOTOCHORD used as a noun is very rare.

 Dictionary entry details 

• NOTOCHORD (noun)

Sense 1

Meaning:

A flexible rodlike structure that forms the supporting axis of the body in the lowest chordates and lowest vertebrates and in embryos of higher vertebrates

Classified under:

Nouns denoting animals

Hypernyms ("notochord" is a kind of...):

back; backbone; rachis; spinal column; spine; vertebral column (the series of vertebrae forming the axis of the skeleton and protecting the spinal cord)

Hyponyms (each of the following is a kind of "notochord"):

urochord (a notochord of a larval tunicate typically confined to the caudal region)

 Context examples 

A slow-growing malignant bone tumor arising from the remnants of the notochord and occurring in the clivus.

(Clivus Chondroid Chordoma, NCI Thesaurus)

A malignant bone tumor arising from the remnants of the fetal notochord.

(Chordoma, NCI Thesaurus)

A slow-growing malignant bone tumor arising from the remnants of the notochord and occurring in the base of the skull.

(Chondroid Chordoma, NCI Thesaurus)

A malignant bone neoplasm arising from the remnants of the fetal notochord.

(Chordoma, NCI Thesaurus/CDISC)

A high-grade malignant bone tumor arising from the remnants of the notochord.

(Dedifferentiated Chordoma, NCI Thesaurus)

Tissue and cells from the general category of the kingdom Animalia (multicellular animals) including those phyla whose members lack a notochord.

(Invertebrate Tissue and Cells, NCI Thesaurus)

BMP signaling can also be blocked by the BMP antagonists noggin and chordin, which are secreted from the notochord and cooperate with Wnts to prevent cardiogenesis.

(ALK Pathway, NCI Thesaurus/BIOCARTA)

A low to intermediate grade malignant tumor that recapitulates notochord.

(Chordoma, NCI Thesaurus)

Inhibitory signals that block heart formation in anterior paraxial mesoderm include Wnt family members expressed in dorsal neural tube and anti-BMPs expressed in the axial tissues (i.e., noggin in the notochord).

(ALK Pathway, NCI Thesaurus/BIOCARTA)