English Dictionary |
NNRTI
Pronunciation (US): | (GB): |
Dictionary entry overview: What does NNRTI mean?
• NNRTI (noun)
The noun NNRTI has 1 sense:
1. an antiviral drug used against HIV; binds directly to reverse transcriptase and prevents RNA conversion to DNA; often used in combination with other drugs
Familiarity information: NNRTI used as a noun is very rare.
Dictionary entry details
Sense 1
Meaning:
An antiviral drug used against HIV; binds directly to reverse transcriptase and prevents RNA conversion to DNA; often used in combination with other drugs
Classified under:
Nouns denoting man-made objects
Synonyms:
NNRTI; non-nucleoside reverse transcriptase inhibitor
Hypernyms ("NNRTI" is a kind of...):
reverse transcriptase inhibitor (an antiviral drug that inhibits the action of reverse transcriptase in retroviruses such as HIV)
Hyponyms (each of the following is a kind of "NNRTI"):
delavirdine; Rescriptor (a non-nucleoside reverse transcriptase inhibitor (trade name Rescriptor) used to treat AIDS and HIV)
nevirapine; Viramune (a non-nucleoside reverse transcriptase inhibitor (trade name Viramune) used to treat AIDS and HIV)
Holonyms ("NNRTI" is a part of...):
drug cocktail; HAART; highly active antiretroviral therapy (a combination of protease inhibitors taken with reverse transcriptase inhibitors; used in treating AIDS and HIV)
Context examples
Emivirine has a structure typical of a nucleoside analog but has been shown to bind directly to the reverse transcriptase and act as an NNRTI.
(Emivirine, NCI Thesaurus)
Etravirine is designed to be active against HIV isolates with mutations that confer resistance to the two most commonly prescribed first-generation NNRTIs.
(Etravirine, NCI Thesaurus)
Dapivirine has activity against wild-type virus strains and strains harboring different NNRTI resistance-inducing mutations and may have direct virucidal activity.
(Dapivirine, NCI Thesaurus)
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