NGF

Pronunciation (US):

(GB):

 Dictionary entry overview: What does NGF mean? 

• NGF (noun)
  The noun NGF has 1 sense:

1. a protein that is involved in the growth of peripheral nerve cells

  Familiarity information: NGF used as a noun is very rare.

 Dictionary entry details 

• NGF (noun)

Sense 1

Meaning:

A protein that is involved in the growth of peripheral nerve cells

Classified under:

Nouns denoting substances

Synonyms:

nerve growth factor; NGF

Hypernyms ("NGF" is a kind of...):

growth factor (a protein that is involved in cell differentiation and growth)

 Context examples 

Other transcription factors involved in NGF responses include Egr and CREB.

(Nerve Growth Factor Pathway, NCI Thesaurus/BIOCARTA)

NGFR binds at low affinity to NGF, BDNF, NTF3, and NTF5.

(Nerve Growth Factor Receptor, NCI Thesaurus)

TRKA, TRKB, and TRKC partners are preferred by NGF, NTF5 and BDNF, and NTF3, respectively.

(Oncogene TRK, NCI Thesaurus)

Human NGF wild-type allele is located in the vicinity of 1p13.1 and is approximately 52 kb in length.

(NGF wt Allele, NCI Thesaurus)

Several reports indicate that neurotrophins remain receptor-bound during the retrograde axonal transport to the cell body, but recently it was reported that retrograde transport of NGF was not required to induce neuronal survival.

(Neuronal Survival Pathway, NCI Thesaurus/BIOCARTA)

Upon administration, fulranumab binds to NGF, preventing its binding to and activation of the NGF receptors TrkA and p75NTR.

(Fulranumab, NCI Thesaurus)

PRMT1 activity is essential for NGF induced PC12 differentiation, and blocking PRMT1 by Box C domain of BTG1 or 2 induces apoptosis.

(BTG Cell Cycle Regulation Pathway, NCI Thesaurus/BIOCARTA)

FGFR-mediated Tyr-phosphorylated FRS2 binds to FGFR1 and GRB2/SOS in response to FGF or NGF.

(FGFR Substrate 2, NCI Thesaurus)

Target cells regulate neuronal survival by producing neurotrophic factors, such as NGF and BDNF, which show sequence similarity.

(Brain-Derived Neurotrophic Factor, NCI Thesaurus)

The neurotrophin family consists of nerve growth factor (NGF), brain derived neurotrophic factor (BDNF), neurotrophin 3 (NT-3), and neurotrophin 4 (NT-4).

(Neurotrophin Signaling Pathway, NCI Thesaurus/KEGG)