NECROSIS

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 Dictionary entry overview: What does necrosis mean? 

• NECROSIS (noun)
  The noun NECROSIS has 1 sense:

1. the localized death of living cells (as from infection or the interruption of blood supply)

  Familiarity information: NECROSIS used as a noun is very rare.

 Dictionary entry details 

• NECROSIS (noun)

Sense 1

Meaning:

The localized death of living cells (as from infection or the interruption of blood supply)

Classified under:

Nouns denoting natural phenomena

Synonyms:

gangrene; mortification; necrosis; sphacelus

Hypernyms ("necrosis" is a kind of...):

death (the permanent end of all life functions in an organism or part of an organism)

Hyponyms (each of the following is a kind of "necrosis"):

myonecrosis (localized death of muscle cell fibers)

Derivation:

necrotic (relating to or affected by necrosis)

 Context examples 

It is characterized by the presence of myofibroblastic hyperchromatic spindle cells, hylanized stroma formation, calcification, necrosis, and a multinodular growth pattern.

(Myofibroma, NCI Thesaurus)

Relating to or affected by necrosis.

(Necrotic, NCI Thesaurus)

Histologically the tumors are highly cellular with nuclear and cellular pleomorphism, endothelial proliferation, mitotic figures, and, often, necrosis.

(Adult Spinal Cord Glioblastoma, NCI Thesaurus)

Hemorrhage and necrosis of the adrenal gland tissue.

(Adrenal Hemorrhage, NCI Thesaurus)

In addition, GM-1 exerts anti-excitotoxic activity, prevents necrosis, and improves neuronal recovery and function.

(Monosialotetrahexosylganglioside, NCI Thesaurus)

Morphologically, it is characterized by the presence of small malignant cells, necrosis, and a high mitotic rate.

(Ampulla of Vater Small Cell Neuroendocrine Carcinoma, NCI Thesaurus)

The diagnosis also depends on findings of tumor necrosis, and vascular endothelial proliferation.

(Mouse Glioblastoma, NCI Thesaurus/MMHCC)

CD70, the ligand for the costimulatory receptor CD27 and a member of the tumor necrosis factor (TNF) family, is found on the surfaces of various types of cancer cells.

(Anti-CD70 Antibody-Drug Conjugate MDX-1203, NCI Thesaurus)

Often there is also an increased vascularity and tumor necrosis.

(Mouse Anaplastic Oligoastrocytoma, NCI Thesaurus/MMHCC)

CD70, the ligand for the costimulatory receptor CD27 and a member of the tumor necrosis factor (TNF) family, is found on renal cell carcinoma (RCC) cells among other cancer cell types.

(Anti-CD70 Monoclonal Antibody MDX-1411, NCI Thesaurus)