NADIR

Pronunciation (US):

(GB):

IPA (US):

 Dictionary entry overview: What does nadir mean? 

• NADIR (noun)
  The noun NADIR has 2 senses:

1. an extreme state of adversity; the lowest point of anything

2. the point below the observer that is directly opposite the zenith on the imaginary sphere against which celestial bodies appear to be projected

  Familiarity information: NADIR used as a noun is rare.

 Dictionary entry details 

• NADIR (noun)

Sense 1

Meaning:

An extreme state of adversity; the lowest point of anything

Classified under:

Nouns denoting stable states of affairs

Synonyms:

low-water mark; nadir

Hypernyms ("nadir" is a kind of...):

adversity; hard knocks; hardship (a state of misfortune or affliction)

Sense 2

Meaning:

The point below the observer that is directly opposite the zenith on the imaginary sphere against which celestial bodies appear to be projected

Classified under:

Nouns denoting spatial position

Hypernyms ("nadir" is a kind of...):

celestial point (a point in the heavens (on the celestial sphere))

Holonyms ("nadir" is a part of...):

celestial sphere; empyrean; firmament; heavens; sphere; vault of heaven; welkin (the apparent surface of the imaginary sphere on which celestial bodies appear to be projected)

Antonym:

zenith (the point above the observer that is directly opposite the nadir on the imaginary sphere against which celestial bodies appear to be projected)

 Context examples 

The nadir of the deceleration occurs after the peak of the uterine contraction, and the time from onset to nadir of the deceleration is greater than or equal to 30 seconds.

(Late Fetal Heart Rate Deceleration, NCI Thesaurus)

The evaluation of the antitumor response shows that the sum of the longest diameters of target and new measurable lesions do not meet the criteria for complete remission, partial response (compared to baseline) or progressive disease (compared to nadir).

(Modified Overall Immune Related Response Criterion, Stable Disease, NCI Thesaurus)

The evaluation of the antitumor response shows that the sum of the longest diameters of target and new measurable lesions increases by at least 20% (compared to nadir), and is confirmed by repeated, consecutive observations at least 4 weeks (normally done at 6 weeks) from the date first documented.

(Modified Overall Immune Related Response Criterion, Progressive Disease, NCI Thesaurus)

The nadir of the deceleration occurs at the same time as the peak of the uterine contraction, and the time from onset to nadir of the deceleration is greater than or equal to 30 seconds.

(Early Fetal Heart Rate Deceleration, NCI Thesaurus)