MUTATE

Pronunciation (US):

(GB):

IPA (US):

 Dictionary entry overview: What does mutate mean? 

• MUTATE (verb)
  The verb MUTATE has 1 sense:

1. undergo mutation

  Familiarity information: MUTATE used as a verb is very rare.

 Dictionary entry details 

• MUTATE (verb)

Present simple: I / you / we / they mutate    ... he / she / it mutates   
Past simple: mutated   
Past participle: mutated   
-ing form: mutating   

Sense 1

Meaning:

Undergo mutation

Classified under:

Verbs of size, temperature change, intensifying, etc.

Context example:

cells mutate

Hypernyms (to "mutate" is one way to...):

change (undergo a change; become different in essence; losing one's or its original nature)

Troponyms (each of the following is one way to "mutate"):

revert (undergo reversion, as in a mutation)

Sentence frame:

Something ----s

Derivation:

mutant (an animal that has undergone mutation)

mutant ((biology) an organism that has characteristics resulting from chromosomal alteration)

mutant (tending to undergo or resulting from mutation)

mutation ((genetics) any event that changes genetic structure; any alteration in the inherited nucleic acid sequence of the genotype of an organism)

mutation ((biology) an organism that has characteristics resulting from chromosomal alteration)

mutative (of or pertaining to or marked by genetic mutation)

 Context examples 

Human infection is still very rare, but the virus that causes the infection in birds might change, or mutate, to more easily infect humans.

(Bird Flu, NIH)

A drug used to treat advanced melanoma that has a mutated (changed) form of a cell protein called BRAF.

(BRAF (V600E) kinase inhibitor RO5185426, NCI Dictionary)

This gene may be mutated (changed) in many types of cancer, which causes a change in the B-RAF protein.

(BRAF gene, NCI Dictionary)

This agent does not bind to most mutated forms of androgen receptors.

(Bicalutamide, NCI Thesaurus)

The ataxia telangiectasia-mutated gene (ATM) encodes a protein kinase that acts as a tumor suppressor.

(ATM Signaling Pathway, NCI Thesaurus/BIOCARTA)

Human oncogene DBL is a mutated form of the MCF.2 cell line derived transforming sequence (MCF2) gene, located at Xq27, which encodes 4 alternative variants of the proto-oncogene DBL protein.

(Oncogene DBL, NCI Thesaurus)

If mutated or overexpressed in a dominant fashion, it can release the cell from normal restraints on growth.

(Oncogene, NCI Thesaurus)

A gene that is a mutated (changed) form of a gene involved in normal cell growth.

(Oncogene, NCI Dictionary)

In turn, ARQ 680 selectively binds to and inhibits the activity of oncogenic B-raf, which may inhibit the proliferation of tumor cells expressing mutated B-raf gene.

(BRAF Inhibitor ARQ 736, NCI Thesaurus)

Mutated forms of BRAF are associated with a number of neoplastic diseases.

(BRAF Inhibitor PLX8394, NCI Thesaurus)