MULTIPLE SCLEROSIS

Pronunciation (US):

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 Dictionary entry overview: What does multiple sclerosis mean? 

• MULTIPLE SCLEROSIS (noun)
  The noun MULTIPLE SCLEROSIS has 1 sense:

1. a chronic progressive nervous disorder involving loss of myelin sheath around certain nerve fibers

  Familiarity information: MULTIPLE SCLEROSIS used as a noun is very rare.

 Dictionary entry details 

• MULTIPLE SCLEROSIS (noun)

Sense 1

Meaning:

A chronic progressive nervous disorder involving loss of myelin sheath around certain nerve fibers

Classified under:

Nouns denoting stable states of affairs

Synonyms:

disseminated multiple sclerosis; disseminated sclerosis; MS; multiple sclerosis

Hypernyms ("multiple sclerosis" is a kind of...):

degenerative disorder (condition leading to progressive loss of function)

induration; sclerosis (any pathological hardening or thickening of tissue)

autoimmune disease; autoimmune disorder (any of a large group of diseases characterized by abnormal functioning of the immune system that causes your immune system to produce antibodies against your own tissues)

Meronyms (parts of "multiple sclerosis"):

demyelination (loss of the myelin covering of some nerve fibers resulting in their impaired function)

 Context examples 

A standardized rating scale developed by John F. Kurtzke in 1983 to measure the level of functioning in people with multiple sclerosis based on a standard neurological examination.

(Kurtzke Functional Systems Scores Questionnaire, NCI Thesaurus)

Rating neurologic impairment in multiple sclerosis: an expanded disability status scale (EDSS).

(Kurtzke Expanded Disability Status Scale Questionnaire, NCI Thesaurus/CDISC)

A drug used to treat advanced prostate cancer that does not respond to hormones, adult acute nonlymphocytic leukemia, and advanced or chronic multiple sclerosis.

(Mitoxantrone, NCI Dictionary)

Affecting more than 2 million people worldwide, multiple sclerosis is a disease for which there is no cure.

(Smoldering spots in the brain may signal severe multiple sclerosis, National Institutes of Health)

However, inflammation in the brain – known as neuroinflammation – has been recognised and linked to many disorders including depression, psychosis and multiple sclerosis.

(Inflammation in the brain linked to several forms of dementia, University of Cambridge)

High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.

(Interleukin-17, NCI Thesaurus/LocusLink)

Disease steps in multiple sclerosis: a simple approach to evaluate disease progression.

(Disease Steps Questionnaire, NCI Thesaurus/CDISC)

A system for quantifying disability in multiple sclerosis (MS).

(Expanded Disability Status Scale, NCI Thesaurus)

A standardized, disease-specific rating scale developed by Cella et al in 1996 to assess quality of life and functional status of individuals with multiple sclerosis.

(Functional Assessment of Multiple Sclerosis Questionnaire, NCI Thesaurus)

Overexpression of the IL12B gene is associated with multiple sclerosis.

(IL12B wt Allele, NCI Thesaurus)