MONOVALENT

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 Dictionary entry overview: What does monovalent mean? 

• MONOVALENT (adjective)
  The adjective MONOVALENT has 2 senses:

1. containing only one kind of antibody

2. having a valence of 1

  Familiarity information: MONOVALENT used as an adjective is rare.

 Dictionary entry details 

• MONOVALENT (adjective)

Sense 1

Meaning:

Containing only one kind of antibody

Attribute:

valence; valency ((biology) a relative capacity to unite or react or interact as with antigens or a biological substrate)

Domain category:

immunology (the branch of medical science that studies the body's immune system)

Antonym:

polyvalent (containing several antibodies each capable of counteracting a specific antigen)

Sense 2

Meaning:

Having a valence of 1

Synonyms:

monovalent; univalent

Attribute:

valence; valency ((chemistry) a property of atoms or radicals; their combining power given in terms of the number of hydrogen atoms (or the equivalent))

Domain category:

chemical science; chemistry (the science of matter; the branch of the natural sciences dealing with the composition of substances and their properties and reactions)

Antonym:

polyvalent (having more than one valence, or having a valence of 3 or higher)

 Context examples 

A monovalent Fab fragment of the mouse monoclonal antibody (MoAb) 96.5, raised against an epitope from human melanoma-associated cell surface marker p97.

(Monoclonal Antibody 96.5 F(ab), NCI Thesaurus)

A monovalent Fab fragment of the mouse monoclonal antibody (MoAb) 8.2 raised against human melanoma-associated cell surface marker p97.

(Monoclonal Antibody 8.2 F(ab), NCI Thesaurus)

A monovalent vaccine containing hemagglutinin (HA) of influenza A (H1N1)-like virus with potential immunomodulating activity.

(Non-Adjuvanted A(H1N1) Influenza Vaccine, NCI Thesaurus)

A humanized monovalent monoclonal antibody directed against the hepatocyte growth factor receptor (c-Met) with potential antineoplastic activity.

(Onartuzumab, NCI Thesaurus)

The monovalent group -OH in such compounds as bases and some acids and alcohols.

(Hydroxyl Group, NCI Thesaurus)

The citrate salt of lithium, a monovalent cation with antimanic activity.

(Lithium Citrate, NCI Thesaurus)

A monovalent cation that is metabolized much like sodium and is important in many cellular functions inside or on the surface of cells.

(Lithium Cation, NCI Thesaurus)

A tri-Fab bispecific monoclonal antibody (BiMoAb) divalent for the carcinoembryonic antigen (CEA) and monovalent for histamine-succinyl-glycine (HSG) peptide-hapten radiolabeled with iodine I 131 (I131) with antigen-binding and radioisotopic activities.

(Iodine I 131-Labeled Anti-CEA/Anti-HSG Bispecific Monoclonal Antibody TF2, NCI Thesaurus)

A tri-Fab bispecific monoclonal antibody (BiMoAb) divalent for the carcinoembryonic antigen (CEA) and monovalent for histamine-succinyl-glycine (HSG) peptide-hapten.

(Anti-CEA/Anti-HSG Bispecific Monoclonal Antibody TF2, NCI Thesaurus)

A chemical group containing the monovalent -N=C=S group.

(Isothiocyanate, NCI Thesaurus)