MONOCLONAL

Pronunciation (US):

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IPA (US):

 Dictionary entry overview: What does monoclonal mean? 

• MONOCLONAL (noun)
  The noun MONOCLONAL has 1 sense:

1. any of a class of antibodies produced in the laboratory by a single clone of cells or a cell line and consisting of identical antibody molecules

  Familiarity information: MONOCLONAL used as a noun is very rare.

• MONOCLONAL (adjective)
  The adjective MONOCLONAL has 1 sense:

1. forming or derived from a single clone

  Familiarity information: MONOCLONAL used as an adjective is very rare.

 Dictionary entry details 

• MONOCLONAL (noun)

Sense 1

Meaning:

Any of a class of antibodies produced in the laboratory by a single clone of cells or a cell line and consisting of identical antibody molecules

Classified under:

Nouns denoting substances

Synonyms:

monoclonal; monoclonal antibody

Hypernyms ("monoclonal" is a kind of...):

antibody (any of a large variety of proteins normally present in the body or produced in response to an antigen which it neutralizes, thus producing an immune response)

Hyponyms (each of the following is a kind of "monoclonal"):

infliximab; Remicade (a monoclonal antibody (trade name Remicade) used to treat Crohn's disease and rheumatoid arthritis; administered by infusion; use and dosage must be determined by a physician)

• MONOCLONAL (adjective)

Sense 1

Meaning:

Forming or derived from a single clone

Classified under:

Relational adjectives (pertainyms)

Pertainym:

clone (a group of genetically identical cells or organisms derived from a single cell or individual by some kind of asexual reproduction)

 Context examples 

ZMapp is composed of 3 different monoclonal antibodies (mAbs).

(Experimental Ebola antibody protects monkeys, NIH)

Also called anti-HGF monoclonal antibody AMG 102.

(AMG 102, NCI Dictionary)

AMG 162 is a type of monoclonal antibody.

(AMG 162, NCI Dictionary)

The form of primary amyloid in amyloidoma is characterized by abnormal deposition of light chain proteins composed of monoclonal immunoglobulin.

(Amyloidoma, NCI Thesaurus)

Anti-mesothelin monoclonal antibody MORAb-009 binds to mesothelin (a protein that is made by some cancer cells) and stops the cells from dividing.

(Amatuximab, NCI Dictionary)

A recombinant DNA-derived humanized monoclonal antibody directed against the cell surface glycoprotein, CD52.

(Alemtuzumab, NCI Thesaurus)

Any monoclonal antibody directed against an alpha-beta T-Cell receptor.

(Alpha-Beta T-Cell Receptor Antibody, NCI Thesaurus)

A chimeric IgG1 monoclonal antibody against human mesothelin with potential anti-tumor activity.

(Amatuximab, NCI Thesaurus)

Several therapeutic agents can be utilized to this end, such as drugs and monoclonal antibodies.

(Metastatic Inhibitory Effect, NCI Thesaurus)

Milatuzumab is a type of monoclonal antibody.

(Milatuzumab, NCI Dictionary)