MINOCYCLINE

Pronunciation (US):

(GB):

 Dictionary entry overview: What does minocycline mean? 

• MINOCYCLINE (noun)
  The noun MINOCYCLINE has 1 sense:

1. tetracycline antibiotic (trade name Minocin) used to treat a variety of bacterial and rickettsial infections

  Familiarity information: MINOCYCLINE used as a noun is very rare.

 Dictionary entry details 

• MINOCYCLINE (noun)

Sense 1

Meaning:

Tetracycline antibiotic (trade name Minocin) used to treat a variety of bacterial and rickettsial infections

Classified under:

Nouns denoting man-made objects

Synonyms:

Minocin; minocycline

Hypernyms ("minocycline" is a kind of...):

Achromycin; tetracycline (an antibiotic (trade name Achromycin) derived from microorganisms of the genus Streptomyces and used broadly to treat infections)

 Context examples 

Minocycline exerts its bacteriostatic effect by binding to the bacterial 30S ribosomal subunit and preventing binding of aminoacyl-tRNA to the mRNA-ribosome complex during protein translation.

(minocycline-EDTA, NCI Thesaurus)

Minocycline binds to the bacterial 30S ribosomal subunit and interferes with the binding of tRNA to the ribosomal complex, thereby inhibiting protein translation in bacteria.

(Minocycline Hydrochloride, NCI Thesaurus)

Detailed experiments with these showed that the antibiotic minocycline was highly effective in preventing hardening of the arteries.

(Cause of hardening of the arteries – and potential treatment – identified, University of Cambridge)

A combination preparation containing minocycline, a broad-spectrum, semi-synthetic tetracycline antibiotic, and ethylenediaminetetraacetate (EDTA) with antimicrobial and anticoagulant activities.

(minocycline-EDTA, NCI Thesaurus)

The hydrochloride salt of minocycline, a broad spectrum long-acting derivative of the antibiotic tetracycline, with antibacterial and anti-inflammatory activities.

(Minocycline Hydrochloride, NCI Thesaurus)

Additionally, using rats with chronic kidney disease, the researchers found that minocycline – a widely-prescribed antibiotic often used to treat acne – could treat hardening of the arteries by preventing the build-up of calcium in the circulatory system.

(Cause of hardening of the arteries – and potential treatment – identified, University of Cambridge)

In addition, minocycline inhibits the inflammatory enzyme 5-lipoxygenase (5LOX) and may impede T cell-microglia interactions; both activities may contribute to minocycline's neuroprotective effects. 5LOX catalyzes the synthesis of inflammatory mediators such as prostaglandins and leukotrienes.

(Minocycline Hydrochloride, NCI Thesaurus)