MINERALOCORTICOID

Pronunciation (US):

(GB):

 Dictionary entry overview: What does mineralocorticoid mean? 

• MINERALOCORTICOID (noun)
  The noun MINERALOCORTICOID has 1 sense:

1. hormone that is one of the steroids of the adrenal cortex that influences the metabolism of sodium and potassium

  Familiarity information: MINERALOCORTICOID used as a noun is very rare.

 Dictionary entry details 

• MINERALOCORTICOID (noun)

Sense 1

Meaning:

Hormone that is one of the steroids of the adrenal cortex that influences the metabolism of sodium and potassium

Classified under:

Nouns denoting substances

Hypernyms ("mineralocorticoid" is a kind of...):

adrenal cortical steroid; corticoid; corticosteroid (a steroid hormone produced by the adrenal cortex or synthesized; administered as drugs they reduce swelling and decrease the body's immune response)

Hyponyms (each of the following is a kind of "mineralocorticoid"):

aldosterone (a corticosteroid hormone that is secreted by the cortex of the adrenal gland; regulates salt (sodium and potassium) and water balance)

 Context examples 

Aldosterone helps regulate electrolyte and fluid balance by binding to mineralocorticoid receptors (MRs), which are located throughout the body.

(NIH findings link aldosterone with alcohol use disorder, National Institutes of Health)

This allele, which encodes cytochrome P450 17A1 protein, plays a role in the synthesis of progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens.

(CYP17A1 wt Allele, NCI Thesaurus)

This gene is involved in mineralocorticoid metabolism.

(CYP11B2 Gene, NCI Thesaurus)

Eplerenone binds to the mineralocorticoid receptor and blocks the binding of aldosterone, thereby decreasing sodium resorption and subsequently increasing water outflow.

(Eplerenone, NCI Thesaurus)

Fludrocortisone is a mineralocorticoid receptor and glucocorticoid receptor agonist that binds to cytoplasmic receptors, translocates to the nucleus and subsequently initiates the transcription of glucocorticoid-responsive genes such as lipocortins to inhibit phospholipase A2.

(Fludrocortisone, NCI Thesaurus)

A spironolactone derivative and a potent aldosterone antagonist on mineralocorticoid biosynthesis with diuretic activity.

(Oxprenoate, NCI Thesaurus)

This allele, which encodes mineralocorticoid receptor protein, plays a role in transcriptional regulation and subsequent gene expression.

(NR3C2 wt Allele, NCI Thesaurus)

Mineralocorticoid receptor (984 aa, ~107 kDa) is encoded by the human NR3C2 gene.

(Mineralocorticoid Receptor, NCI Thesaurus)

Clazolimine antagonizes aldosterone at the mineralocorticoid receptor in the kidneys, thereby increasing sodium excretion and inhibiting potassium excretion.

(Clazolimine, NCI Thesaurus)

A synthetic spironolactone analogue and progestin with progestational and anti-mineralocorticoid activity.

(Drospirenone, NCI Thesaurus)