MEXILETINE

Pronunciation (US):

(GB):

 Dictionary entry overview: What does mexiletine mean? 

• MEXILETINE (noun)
  The noun MEXILETINE has 1 sense:

1. antiarrhythmic drug (trade name Mexitil) used to treat ventricular arrhythmias

  Familiarity information: MEXILETINE used as a noun is very rare.

 Dictionary entry details 

• MEXILETINE (noun)

Sense 1

Meaning:

Antiarrhythmic drug (trade name Mexitil) used to treat ventricular arrhythmias

Classified under:

Nouns denoting man-made objects

Synonyms:

mexiletine; Mexitil

Hypernyms ("mexiletine" is a kind of...):

antiarrhythmic; antiarrhythmic drug; antiarrhythmic medication (a drug used to treat an abnormal heart rhythm)

 Context examples 

The hydrochloride salt form of mexiletine, a local anesthetic and antiarrhythmic (Class IB) agent structurally related to lidocaine.

(Mexiletine Hydrochloride, NCI Thesaurus)

Mexiletine's anesthetic activity is due to its ability to block sodium influx in peripheral nerves, thereby reducing the rate and intensity of pain impulses reaching the central nervous system.

(Mexiletine, NCI Thesaurus)

Mexiletine exerts its antiarrhythmic effect by inhibiting the inward sodium current in cardiac cells, thereby reducing the rate of rise of the cardiac action potential (phase 0) and decreases automaticity in the Purkinje fibers.

(Mexiletine, NCI Thesaurus)