METHYLENE

Pronunciation (US):

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 Dictionary entry overview: What does methylene mean? 

• METHYLENE (noun)
  The noun METHYLENE has 1 sense:

1. the bivalent radical CH2 derived from methane

  Familiarity information: METHYLENE used as a noun is very rare.

 Dictionary entry details 

• METHYLENE (noun)

Sense 1

Meaning:

The bivalent radical CH2 derived from methane

Classified under:

Nouns denoting substances

Synonyms:

methylene; methylene group; methylene radical

Hypernyms ("methylene" is a kind of...):

chemical group; group; radical ((chemistry) two or more atoms bound together as a single unit and forming part of a molecule)

 Context examples 

An amino acid derivative and homolog of cysteine containing an additional methylene bridge.

(Homocysteine, NCI Thesaurus)

Methylene dimethane sulfonate alkylates DNA, resulting in interstrand DNA crosslinking, inhibition of DNA replication, disruption of the cell cycle, and cell death.

(Methylene Dimethane Sulfonate, NCI Thesaurus)

Methylene chloride is a possible mutagen and is reasonably anticipated to be a human carcinogen.

(Methylene Chloride, NCI Thesaurus)

LNAs contain a methylene bridge linking 2'-oxygen and 4'-carbon of ribose sugar rings, thereby increasing their thermal stability and decreasing degradation.

(Androgen Receptor Antisense Oligonucleotide EZN-4176, NCI Thesaurus)

Cells are methylene blue positive on whole-mount sections of the intestinal mucosa.

(Aberrant Crypt Foci of the Mouse Intestinal Tract, NCI Thesaurus)

Cells are methylene blue positive on whole mounts, cells have basophilic cytoplasm on H and E stain, and may have Beta-catenin staining in the nucleus.

(Aberrant Crypt Foci of the Mouse Intestinal Tract, NCI Thesaurus/MMHCC)

In 2015, medical researchers in India held methylene cyclopropyl-glycine (MCPG) — a toxic phytochemical found in the lychee fruit — responsible for outbreaks of AES in India’s Bihar state.

(Lychee deaths linked to pesticides, not the fruit, SciDev.Net)

Although the exact mechanism through which clodronic acid exerts its cytotoxic effect on osteoclasts has yet to be fully elucidated, this agent is metabolized intracellularly to a toxic beta-gamma-methylene analog of adenosine triphosphate (ATP), AppCCl2p.

(Clodronic Acid, NCI Thesaurus)

Methylene blue stains to negatively charged cell components like nucleic acids; when administered in the lymphatic bed of a tumor during oncologic surgery, methylene blue may stain lymph nodes draining from the tumor, thereby aiding in the visual localization of tumor sentinel lymph nodes.

(Methylene Blue, NCI Thesaurus)

Methylene chloride is primarily used as a solvent in paint removers, but is also used in aerosol formulations, as a solvent in the manufacture of pharmaceuticals, as a degreasing agent, in electronics manufacturing and as an ethane foam blowing agent.

(Methylene Chloride, NCI Thesaurus)