METHICILLIN

Pronunciation (US):

(GB):

 Dictionary entry overview: What does methicillin mean? 

• METHICILLIN (noun)
  The noun METHICILLIN has 1 sense:

1. antibiotic drug of the penicillin family used in the treatment of certain staphylococcal infections

  Familiarity information: METHICILLIN used as a noun is very rare.

 Dictionary entry details 

• METHICILLIN (noun)

Sense 1

Meaning:

Antibiotic drug of the penicillin family used in the treatment of certain staphylococcal infections

Classified under:

Nouns denoting man-made objects

Hypernyms ("methicillin" is a kind of...):

penicillin (any of various antibiotics obtained from Penicillium molds (or produced synthetically) and used in the treatment of various infections and diseases)

 Context examples 

To overcome this, drug manufacturers developed new derivatives of penicillin, such as methicillin, which were resistant to beta-lactamase.

(Widely-available antibiotics could be used in the treatment of ‘superbug’ MRSA, University of Cambridge)

Ceftaroline fosamil, when hydrolyzed to the active form ceftaroline, has a high affinity for penicillin binding protein 2a (PBP2a), which is associated with methicillin resistance.

(Ceftaroline Fosamil Acetate, NCI Thesaurus)

Second-generation penicillins, such as methicillin, were resistant to those enzymes.

(Antibiotic Combinations May Combat MRSA Infections, NIH)

Methicillin sodium is active against beta-lactamase producing staphylococci.

(Methicillin Sodium, NCI Thesaurus)

Methicillin binds to specific penicillin-binding proteins (BPBs) on the bacterial cell wall, thereby preventing the cross-linkage of peptidoglycans, which are critical components of the bacterial cell wall.

(Methicillin, NCI Thesaurus)

Researchers have known of tunicamycin for decades and were initially excited by its medical and veterinary prospects—especially as a way to overcome the resistance of some germs to penicillin-based drugs like oxacillin and methicillin.

(Soil Bacterium Tapped for Penicillin Guard Duty, U.S. Department of Agriculture)

Methicillin sodium is bactericidal and binds to specific penicillin-binding proteins on the bacterium and inhibits the transpeptidation enzyme, thereby preventing the cross-linking of peptidoglycans.

(Methicillin Sodium, NCI Thesaurus)

The sodium salt form of methicillin, a semisynthetic beta-lactam penicillin antibiotic with beta-lactamase resistant activity.

(Methicillin Sodium, NCI Thesaurus)