METABOLITE

Pronunciation (US):

(GB):

 Dictionary entry overview: What does metabolite mean? 

• METABOLITE (noun)
  The noun METABOLITE has 1 sense:

1. any substance involved in metabolism (either as a product of metabolism or as necessary for metabolism)

  Familiarity information: METABOLITE used as a noun is very rare.

 Dictionary entry details 

• METABOLITE (noun)

Sense 1

Meaning:

Any substance involved in metabolism (either as a product of metabolism or as necessary for metabolism)

Classified under:

Nouns denoting substances

Hypernyms ("metabolite" is a kind of...):

substance (a particular kind or species of matter with uniform properties)

 Context examples 

Acetohexamide is metabolized in the liver to its active metabolite hydroxyhexamide.

(Acetohexamide, NCI Thesaurus)

An orally-active metabolite of the synthetic aromatic retinoic acid agent etretinate with potential antineoplastic, chemopreventive, anti-psoratic, and embryotoxic properties.

(Acitretin, NCI Thesaurus)

An active metabolite of NV-128, a novel flavonoid small molecule inhibitor of the mammalian Target of Rapamycin (mTOR), with potential antineoplastic activity.

(mTOR1/2 Kinase Inhibitor ME-344, NCI Thesaurus)

NR acts on the brain by normalizing levels of nicotinamide adenine dinucleotide (NAD+), a metabolite vital to cellular energy, stem cell self-renewal, resistance to neuronal stress and DNA repair.

(Compound prevents neurological damage, shows cognitive benefits in mouse model of Alzheimer’s disease, National Institutes of Health)

The researchers measured a number of effects in the muscle cells, including the transcriptional response and effects on the metabolites.

(Morning, Evening Exercise Provides Different Health Benefits, The Titi Tudorancea Bulletin)

MKC-1 and its metabolites inhibit tubulin polymerization, blocking the formation of the mitotic spindle, which may result in cell cycle arrest at the G2/M phase and apoptosis.

(MKC-1, NCI Thesaurus)

These metabolites are excreted in urine that maybe used as indicators for pituitary responsiveness.

(Metyrapone, NCI Thesaurus)

A measurement of the androstenediol metabolite in a biological specimen.

(Androstenediol Metabolite Measurement, NCI Thesaurus/CDISC)

The active metabolites alkylate DNA, resulting in apoptotic cell death.

(Apaziquone, NCI Thesaurus)

The determination of the amount of androstenediol metabolite present in a sample.

(Androstenediol Metabolite Measurement, NCI Thesaurus)