MENADIONE

Pronunciation (US):

(GB):

 Dictionary entry overview: What does menadione mean? 

• MENADIONE (noun)
  The noun MENADIONE has 1 sense:

1. a form of vitamin K

  Familiarity information: MENADIONE used as a noun is very rare.

 Dictionary entry details 

• MENADIONE (noun)

Sense 1

Meaning:

A form of vitamin K

Classified under:

Nouns denoting substances

Synonyms:

menadione; vitamin K3

Hypernyms ("menadione" is a kind of...):

antihemorrhagic factor; naphthoquinone; vitamin K (a fat-soluble vitamin that helps in the clotting of blood)

 Context examples 

A topical lotion containing the small organic molecule protein tyrosine phosphatase (PTP) inhibitor menadione (vitamin K3) with potential EGFR- and ErbB2/HER2-activating activities.

(Menadione Topical Lotion, NCI Thesaurus)

This protein plays a role in the reduction of cytochrome c, doxorubicin, potassium ferricyanide and menadione.

(NADPH-Dependent Diflavin Oxidoreductase 1, NCI Thesaurus)

Upon topical administration, menadione binds to and inhibits the activity of PTPs that dephosphorylate and inactivate EGFR and ErbB2 in human keratinocytes; local reversal of EGFR and ErbB2 inhibition associated with the systemic administration of EGFR inhibitors may help alleviate EGFR inhibitor-mediated skin toxicity.

(Menadione Topical Lotion, NCI Thesaurus)