MEGAKARYOCYTE

Pronunciation (US):

(GB):

 Dictionary entry overview: What does megakaryocyte mean? 

• MEGAKARYOCYTE (noun)
  The noun MEGAKARYOCYTE has 1 sense:

1. a large bone marrow cell; regarded as the source of blood platelets

  Familiarity information: MEGAKARYOCYTE used as a noun is very rare.

 Dictionary entry details 

• MEGAKARYOCYTE (noun)

Sense 1

Meaning:

A large bone marrow cell; regarded as the source of blood platelets

Classified under:

Nouns denoting body parts

Hypernyms ("megakaryocyte" is a kind of...):

bone cell (a cell that is part of a bone)

Derivation:

megakaryocytic (of or pertaining to large bone marrow cells)

 Context examples 

CFU-GEMM cells are a key intermediate in the differentiation of granulocytes, erythrocytes, monocytes and megakaryocytes.

(Erythrocyte Differentiation Pathway, NCI Thesaurus/BIOCARTA)

Also called PEG-MGDF and polyethylene glycosylated recombinant human megakaryocyte growth and development factor.

(PEG-rhMGDF, NCI Dictionary)

Without morphologic dysgranulopoiesis, dyserythropoiesis, or dysplastic megakaryocytes; greater or equal to 20% myeloid immature forms/blasts in bone marrow and/or spleen

(Cytopenia with Increased Blasts of Mouse, NCI Thesaurus/MMHCC)

A rare disorder of infancy characterized by marked reduction or absence of megakaryocytes and thrombocytopenia.

(Congenital Amegakaryocytosis, NCI Thesaurus)

The bone marrow is usually hypercellular or normocellular with increased number of often hypolobated megakaryocytes.

(Myelodysplastic Syndrome with Isolated del(5q), NCI Thesaurus/WHO)

A form of megakaryocyte growth and development factor (MGDF) that is made in the laboratory.

(PEG Recombinant Human Megakaryocyte Growth and Development Factor, NCI Dictionary)

Platelets are not blood cells, they are fragments of large bone marrow cells called megakaryocytes.

(Platelet, NCI Thesaurus)

A progressive, proliferative disease of blood cells, originating from immature megakaryocytes.

(Acute Megakaryoblastic Leukemia, NCI Thesaurus/CDISC)

It supports proliferation of both hematopoietic stem cells and megakaryocyte progenitor cells and regulates bone marrow adipogenesis.

(Interleukin-11, NCI Thesaurus)

This gene plays a role in cell adhesion, megakaryocyte differentiation, apoptosis regulation and calcium binding.

(CIB1 Gene, NCI Thesaurus)