English Dictionary

MARKEDLY

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IPA (US): 

 Dictionary entry overview: What does markedly mean? 

MARKEDLY (adverb)
  The adverb MARKEDLY has 1 sense:

1. in a clearly noticeable mannerplay

  Familiarity information: MARKEDLY used as an adverb is very rare.


 Dictionary entry details 


MARKEDLY (adverb)


Sense 1

Meaning:

In a clearly noticeable manner

Context example:

sales of luxury cars dropped markedly

Pertainym:

marked (strongly marked; easily noticeable)


 Context examples 


The most significant factor associated with recurrence is the extent of surgical resection, with lesions greater than 5 cm in diameter carrying a markedly worse prognosis.

(Craniopharyngioma, NCI Thesaurus/Adapted from WHO)

Compared to adults who were born at a normal weight, those born at an extremely low weight had higher rates of anxiety and depression, and markedly lower levels of social functioning.

(Tiny Babies May Face Mental Health Problems Later, The Titi Tudorancea Bulletin)

The team’s analysis showed that the intestinal microbiota in regular-fed mutant mice was markedly different from that of healthy wild-type mice.

(Diet Affects Autoinflammatory Disease Via Gut Microbes, NIH)

A neoplasm of the skin composed of cells with markedly granular cytoplasm that exhibit strong S100 immunoperoxidase positivity.

(Granular Cell Tumor of the Mouse Skin, NCI Thesaurus/MMHCC)

A morphologic variant of angioleiomyoma characterized by the presence of markedly dilated vascular channels.

(Cavernous Angioleiomyoma, NCI Thesaurus)

The results of the positron emission tomography are positive; the tracer uptake is markedly increased at any disease site.

(London Deauville Criteria Point Scale 5, NCI Thesaurus)

Air temperatures over the bay, though they had generally warmed over past decades, they hadn't spiked markedly in 2008 to 2012.

(Wind, Warm Water Revved Up Melting Antarctic Glaciers, NASA)

As a result, loxoribine induces cycling B cells to proliferate and differentiate non-specifically and recruit antigen-reactive B cells to undergo differentiation to antibody production, markedly amplifying the underlying response in the process.

(Loxoribine, NCI Thesaurus)

They can vary markedly in size and color.

(Neurofibromatosis type 1, NCI Thesaurus)

The valine to glutamic acid substitution at residue 600 accounts for about 90% of BRAF gene mutations; the oncogenic product, BRAF(V600E) kinase, exhibits a markedly elevated activity that over-activates the MAPK signaling pathway.

(BRAF(V600E) Kinase Inhibitor RO5212054, NCI Thesaurus)



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