LYMPHOKINE

Pronunciation (US):

(GB):

 Dictionary entry overview: What does lymphokine mean? 

• LYMPHOKINE (noun)
  The noun LYMPHOKINE has 1 sense:

1. a cytokine secreted by helper T cells in response to stimulation by antigens and that acts on other cells of the immune system (as by activating macrophages)

  Familiarity information: LYMPHOKINE used as a noun is very rare.

 Dictionary entry details 

• LYMPHOKINE (noun)

Sense 1

Meaning:

A cytokine secreted by helper T cells in response to stimulation by antigens and that acts on other cells of the immune system (as by activating macrophages)

Classified under:

Nouns denoting substances

Hypernyms ("lymphokine" is a kind of...):

cytokine (any of various protein molecules secreted by cells of the immune system that serve to regulate the immune system)

Hyponyms (each of the following is a kind of "lymphokine"):

interleukin (any of several lymphokines that promote macrophages and killer T cells and B cells and other components of the immune system)

 Context examples 

This gene is involved in growth and lymphokine regulation.

(IL2 Gene, NCI Thesaurus)

The cytotoxic activity of Natural Killer cells (NK cells) and lymphokine activated killer cells (LAK cells) toward viral infected or tumor cells is stimulated by IL-2 and other cytokines.

(Inflammatory Response Pathway, NCI Thesaurus/BIOCARTA)

Secreted by activated natural killer lymphocytes as a 50-kDa glycoprotein lymphokine, Leukoregulin can up regulate the expression of hyaluronan and prostaglandin-endoperoxide H synthase 2 (PTGS2), the inflammatory cyclooxygenase.

(Leukoregulin, NCI Thesaurus)

Interleukin lymphokines, targeted to cells of hematopoietic origin, are not secreted by leukocytes but affect the cellular responses of leukocytes.

(Cytokine Receptor Gene, NCI Thesaurus)

Those manifestations of the immune response which are mediated by antigen-sensitized T-lymphocytes via lymphokines or direct cytotoxicity.

(Cell-Mediated Immunity, NCI Thesaurus)

Cyclosporine also inhibits lymphokine production and release.

(Cyclosporine, NCI Thesaurus)

Immunity mediated by T-lymphocytes through either release of lymphokines or exertion of direct cytotoxicity; responsible for reactions such as allograft rejection and delayed hypersensitivity.

(Cell-Mediated Immunity, NIH CRISP Thesaurus)

Cytokines are secreted by inflammatory leukocytes (lymphokines), by monocytes or macrophages (monokines), and by various other cells.

(Cytokine Receptor Gene, NCI Thesaurus)