LOVASTATIN

Pronunciation (US):

(GB):

IPA (US):

 Dictionary entry overview: What does lovastatin mean? 

• LOVASTATIN (noun)
  The noun LOVASTATIN has 1 sense:

1. an oral drug (trade name Mevacor) to reduce blood cholesterol levels; used when dietary changes have proved inadequate

  Familiarity information: LOVASTATIN used as a noun is very rare.

 Dictionary entry details 

• LOVASTATIN (noun)

Sense 1

Meaning:

An oral drug (trade name Mevacor) to reduce blood cholesterol levels; used when dietary changes have proved inadequate

Classified under:

Nouns denoting man-made objects

Synonyms:

lovastatin; Mevacor

Hypernyms ("lovastatin" is a kind of...):

lipid-lowering medication; lipid-lowering medicine; statin; statin drug (a medicine that lowers blood cholesterol levels by inhibiting HMG-CoA reductase)

 Context examples 

The active, acid form of lovastatin.

(Lovastatin Acid, NCI Thesaurus)

The statins such as lovastatin are drugs that inhibit cholesterol biosynthesis, lowering intracellular cholesterol levels and activating SREBP cleavage to increase LDLR expression on the cell surface.

(Lipid Synthesis Pathway, NCI Thesaurus/BIOCARTA)

Lovastatin is hydrolyzed to the active beta-hydroxyacid form, which competitively inhibits 3-hydroxyl-3-methylgutarylcoenzyme A (HMG-CoA) reductase, an enzyme involved in cholesterol biosynthesis.

(Lovastatin, NCI Thesaurus)

Lovastatin is a type of HMG-CoA reductase inhibitor (statin).

(Lovastatin, NCI Dictionary)

Also called lovastatin.

(Mevacor, NCI Dictionary)

In the body lovastatin is hydrolysed to its beta-hydroxy acid active form.

(Lovastatin Acid, NCI Thesaurus)