LOMUSTINE

Pronunciation (US):

(GB):

 Dictionary entry overview: What does lomustine mean? 

• LOMUSTINE (noun)
  The noun LOMUSTINE has 1 sense:

1. an antineoplastic drug often used to treat brain tumors or Hodgkin's disease

  Familiarity information: LOMUSTINE used as a noun is very rare.

 Dictionary entry details 

• LOMUSTINE (noun)

Sense 1

Meaning:

An antineoplastic drug often used to treat brain tumors or Hodgkin's disease

Classified under:

Nouns denoting man-made objects

Hypernyms ("lomustine" is a kind of...):

antineoplastic; antineoplastic drug; cancer drug (any of several drugs that control or kill neoplastic cells; used in chemotherapy to kill cancer cells; all have unpleasant side effects that may include nausea and vomiting and hair loss and suppression of bone marrow function)

 Context examples 

A regimen consisting of procarbazine, lomustine (CCNU) and vincristine used for the treatment of low grade, adult oligodendroglial tumors.

(PCV Regimen, NCI Thesaurus)

Lomustine is lipophilic and crosses the blood-brain barrier.

(Lomustine, NCI Thesaurus)

Lomustine damages the cell's DNA and may kill cancer cells.

(Lomustine, NCI Dictionary)

Also called CCNU and lomustine.

(CeeNU, NCI Dictionary)

Carmustine and lomustine are nitrosoureas.

(Nitrosourea, NCI Dictionary)

Also called CeeNU and lomustine.

(CCNU, NCI Dictionary)

Lomustine alkylates and crosslinks DNA, thereby inhibiting DNA and RNA synthesis.

(Lomustine, NCI Thesaurus)