LIGAND

Pronunciation (US):

(GB):

IPA (US):

 Dictionary entry overview: What does ligand mean? 

• LIGAND (noun)
  The noun LIGAND has 1 sense:

1. a substance (an atom or molecule or radical or ion) that forms a complex around a central atom

  Familiarity information: LIGAND used as a noun is very rare.

 Dictionary entry details 

• LIGAND (noun)

Sense 1

Meaning:

A substance (an atom or molecule or radical or ion) that forms a complex around a central atom

Classified under:

Nouns denoting substances

Hypernyms ("ligand" is a kind of...):

substance (a particular kind or species of matter with uniform properties)

 Context examples 

This protein is involved in both ligand binding and signal transduction.

(Myelin Protein Zero-Like 1, NCI Thesaurus)

An amonafide (naphthalimide) derivative and pan-antagonist of chemokine ligand (CXCL) expression, with potential anti-angiogenic activity.

(Naphthalimide Analogue UNBS5162, NCI Thesaurus)

Anti-RON monoclonal antibody IMC-RON8 binds to RON, thereby preventing binding of its ligand hepatocyte growth factor-like protein (HGFL or macrophage-stimulating protein (MSP)).

(Narnatumab, NCI Thesaurus)

Necitumumab binds to and blocks the ligand binding site of EGFR, thereby preventing the activation and subsequent dimerization of the receptor.

(Necitumumab, NCI Thesaurus)

An adenovirus vector engineered to produce CD40 ligand.

(Adenovirus 5-CD40 Ligand, NCI Thesaurus)

The adjuvant poly-ICLC, a ligand for toll-like receptor-3, induces the release of cytokines which may help boost the immune response against MUC1.

(MUC1 Peptide-Poly-ICLC Vaccine, NCI Thesaurus)

This protein is involved in ligand binding, tyrosine phosphorylation and signal transduction.

(ALK Tyrosine Kinase Receptor, NCI Thesaurus)

The team learned to attach ligands, which help bind molecules together, to a nanoparticle.

(Making higher energy light to fight cancer, National Science Foundation)

This protein plays a role in both ligand recognition and signal transduction.

(Melatonin Receptor Type 1B, NCI Thesaurus)

The most important positive regulator of melanogenesis is the MC1 receptor with its ligands melanocortic peptides.

(Melanogenesis Pathway, NCI Thesaurus/KEGG)