KINASE

Pronunciation (US):

(GB):

 Dictionary entry overview: What does kinase mean? 

• KINASE (noun)
  The noun KINASE has 1 sense:

1. an enzyme that catalyzes the conversion of a proenzyme to an active enzyme

  Familiarity information: KINASE used as a noun is very rare.

 Dictionary entry details 

• KINASE (noun)

Sense 1

Meaning:

An enzyme that catalyzes the conversion of a proenzyme to an active enzyme

Classified under:

Nouns denoting substances

Hypernyms ("kinase" is a kind of...):

enzyme (any of several complex proteins that are produced by cells and act as catalysts in specific biochemical reactions)

 Context examples 

This gene plays a role in the transforming growth factor-beta signal transduction pathway and is essential for ligand binding and kinase activity.

(ACVR2B Gene, NCI Thesaurus)

This allele, which encodes serine/threonine-protein kinase receptor R3 protein, is involved in receptor signal transduction.

(ACVRL1 wt Allele, NCI Thesaurus)

This gene plays a role in the transforming growth factor-beta signal transduction pathway through constitutive kinase activity.

(ACVR2A Gene, NCI Thesaurus)

Menatetrenone may act by modulating the signalling of certain tyrosine kinases, thereby affecting several transcription factors including c-myc and c-fos.

(Menatetrenone, NCI Thesaurus)

Both AMP-activated protein kinase (AMPK) and AMPK kinase (AMPKK) are activated by ZMP, which appears to be necessary for the induction of apoptosis.

(Acadesine, NCI Thesaurus)

An inhibitor of MET tyrosine kinase with potential antineoplastic activity.

(MET Tyrosine Kinase Inhibitor BMS-777607, NCI Thesaurus)

The SCF activation of Kit receptor leads to Mitf phosphorylation through the MAP kinase pathway.

(Melanocyte Development Pathway, NCI Thesaurus/BIOCARTA)

Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (1455 aa, ~159 kDa) is encoded by the human MAGI2 gene.

(Membrane-Associated Guanylate Kinase, WW and PDZ Domain-Containing Protein 2, NCI Thesaurus)

The investigators found that mutations in a gene called leucine-rich repeat kinase 2 (LRRK2) may increase the rate at which LRRK2 tags ribosomal proteins, which are key components of protein-making machinery inside cells.

(Too much protein may kill brain cells as Parkinson’s progresses, NINDS)

Schwannomin interacts with the HGF-regulated tyrosine kinase substrate HRS.

(Merlin, NCI Thesaurus)