IR

Pronunciation (US):

(GB):

 Dictionary entry overview: What does IR mean? 

• IR (noun)
  The noun IR has 2 senses:

1. a heavy brittle metallic element of the platinum group; used in alloys; occurs in natural alloys with platinum or osmium

2. a board of the British government that administers and collects major direct taxes

  Familiarity information: IR used as a noun is rare.

 Dictionary entry details 

• IR (noun)

Sense 1

Meaning:

A heavy brittle metallic element of the platinum group; used in alloys; occurs in natural alloys with platinum or osmium

Classified under:

Nouns denoting substances

Synonyms:

atomic number 77; Ir; iridium

Hypernyms ("Ir" is a kind of...):

metal; metallic element (any of several chemical elements that are usually shiny solids that conduct heat or electricity and can be formed into sheets etc.)

Sense 2

Meaning:

A board of the British government that administers and collects major direct taxes

Classified under:

Nouns denoting groupings of people or objects

Synonyms:

Inland Revenue; IR

Hypernyms ("IR" is a kind of...):

administrative body; administrative unit (a unit with administrative responsibilities)

Domain region:

Britain; Great Britain; U.K.; UK; United Kingdom; United Kingdom of Great Britain and Northern Ireland (a monarchy in northwestern Europe occupying most of the British Isles; divided into England and Scotland and Wales and Northern Ireland; 'Great Britain' is often used loosely to refer to the United Kingdom)

 Context examples 

IGF-R1 and IR tyrosine kinases, overexpressed in a variety of human cancers, play significant roles in the stimulation of cellular proliferation, oncogenic transformation, and suppression of apoptosis.

(IGF-1R/IR Inhibitor KW-2450, NCI Thesaurus)

Insulin forms a complex with the insulin receptor (IR) and b chains to form the active signaling complex.

(Insulin Signaling Pathway, NCI Thesaurus/BIOCARTA)

Hydrostat IR is made from morphine and binds to opioid receptors in the central nervous system.

(Hydrostat IR, NCI Dictionary)

Also called Dilaudid, Exalgo, and Hydrostat IR.

(Hydromorphone hydrochloride, NCI Dictionary)

Also called Exalgo, hydromorphone hydrochloride, and Hydrostat IR.

(Dilaudid, NCI Dictionary)

Also called Dilaudid, hydromorphone hydrochloride, and Hydrostat IR.

(Exalgo, NCI Dictionary)

Dual IGF-IR/InsR inhibitor BMS-754807 binds reversibly to and inhibits the activities of IGF-1R and InsR, which may result in the inhibition of tumor cell proliferation and the induction of tumor cell apoptosis.

(Dual IGF-1R/InsR Inhibitor BMS-754807, NCI Thesaurus)

Through recruitment of adaptor molecules and the activation of RAS, the activated IR can cause transcriptional activation.

(Insulin Signaling Pathway, NCI Thesaurus/BIOCARTA)

An orally bioavailable inhibitor of insulin-like growth factor 1 receptor (IGF-1R) and insulin receptor (IR) tyrosine kinases with potential antineoplastic activity.

(IGF-1R/IR Inhibitor KW-2450, NCI Thesaurus)

IGF-1R/IR inhibitor KW-2450 selectively binds to and inhibits the activities of IGF-1R and IR, which may result in the inhibition of tumor cell proliferation and the induction of tumor cell apoptosis.

(IGF-1R/IR Inhibitor KW-2450, NCI Thesaurus)