INVARIANT

Pronunciation (US):

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 Dictionary entry overview: What does invariant mean? 

• INVARIANT (noun)
  The noun INVARIANT has 1 sense:

1. a feature (quantity or property or function) that remains unchanged when a particular transformation is applied to it

  Familiarity information: INVARIANT used as a noun is very rare.

• INVARIANT (adjective)
  The adjective INVARIANT has 2 senses:

1. unaffected by a designated operation or transformation

2. unvarying in nature

  Familiarity information: INVARIANT used as an adjective is rare.

 Dictionary entry details 

• INVARIANT (noun)

Sense 1

Meaning:

A feature (quantity or property or function) that remains unchanged when a particular transformation is applied to it

Classified under:

Nouns denoting cognitive processes and contents

Hypernyms ("invariant" is a kind of...):

characteristic; feature (a prominent attribute or aspect of something)

Domain category:

math; mathematics; maths (a science (or group of related sciences) dealing with the logic of quantity and shape and arrangement)

• INVARIANT (adjective)

Sense 1

Meaning:

Unaffected by a designated operation or transformation

Similar:

invariable (not liable to or capable of change)

Domain category:

math; mathematics; maths (a science (or group of related sciences) dealing with the logic of quantity and shape and arrangement)

Derivation:

invariance (the nature of a quantity or property or function that remains unchanged when a given transformation is applied to it)

Sense 2

Meaning:

Unvarying in nature

Synonyms:

changeless; constant; invariant; unvarying

Context example:

principles of unvarying validity

Similar:

invariable (not liable to or capable of change)

Derivation:

invariance (the quality of being resistant to variation)

 Context examples 

N-terminal domain 1 and C-terminal domain 3 contain invariant cysteine residues and are thought to be the IGF binding domains.

(Insulin-Like Growth Factor-Binding Protein 2, NCI Thesaurus)

The portion of an antibody that is invariant within a class of immunoglobulins.

(Immunoglobulin Constant Region, NCI Thesaurus)

Method for identifying invariant set normalization baseline using mean expression values.

(Mean Baseline Removal Method, NCI Thesaurus)

Method for identifying invariant set normalization baseline using median expression values.

(Median Baseline Removal Method, NCI Thesaurus)

The NOVA2 KH3 domain interacts with single-stranded RNA; KH3 bound to stem loop RNA resembles a vise, with UCAC held between an invariant Gly-X-X-Gly motif and a variable loop.

(Neuro-Oncological Ventral Antigen 2, NCI Thesaurus)

The heterodimer consists of 4 extracellular domains; invariant alpha-1, polymorphic N-terminal beta-1, and conserved Ig-like alpha-2 and beta-2.

(HLA-DR Antigen, NCI Thesaurus)

Loop residues 1, 3, 5, 7, 9, and 12 (invariant Glu or Asp) are directly necessary for Ca2+ binding.

(EF-Hand Domain, NCI Thesaurus)

A method which relies on identifying invariant sets of features across arrays, and using these to perform normalization.

(Baseline Removal Method, NCI Thesaurus)

The CYP2C19*7 allele exhibits a clinically-relevant SNP (c.IVS5+2T>A) in the invariant GT at the 5' donor splice site of intron 5 that results in a splicing defect.

(CYP2C19*7 Allele, NCI Thesaurus)

The class II-associated invariant chain peptide (CLIP) region (residues 81-104) of Ii is believed to mediate this inhibition by engaging the binding domain of class II like an antigenic peptide.

(Antigen Presentation Pathway, NCI Thesaurus/BIOCARTA)