INTERNALIZE

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 Dictionary entry overview: What does internalize mean? 

• INTERNALIZE (verb)
  The verb INTERNALIZE has 1 sense:

1. incorporate within oneself; make subjective or personal

  Familiarity information: INTERNALIZE used as a verb is very rare.

 Dictionary entry details 

• INTERNALIZE (verb)

Present simple: I / you / we / they internalize    ... he / she / it internalizes   
Past simple: internalized   
Past participle: internalized   
-ing form: internalizing   

Sense 1

Meaning:

Incorporate within oneself; make subjective or personal

Classified under:

Verbs of thinking, judging, analyzing, doubting

Synonyms:

interiorise; interiorize; internalise; internalize

Context example:

internalize a belief

Hypernyms (to "internalize" is one way to...):

ascribe; assign; attribute; impute (attribute or credit to)

Domain category:

psychological science; psychology (the science of mental life)

Sentence frames:

Somebody ----s something
Somebody ----s something PP

Derivation:

internalization (learning (of values or attitudes etc.) that is incorporated within yourself)

 Context examples 

These macrophages continue to internalize LDL, becoming enlarged and full of lipid.

(LDL Pathway, NCI Thesaurus/BIOCARTA)

So, in her latest work, she developed a new way to test just how much BPA people are exposed to and internalizing.

(Humans exposed to far more hormone-disrupting chemicals than thought, The Titi Tudorancea Bulletin)

Following binding, monoclonal antibody G250 (mAb G250) may be internalized by G250 antigen-expressing renal carcinoma cells; mAb G250 may be useful as a carrier for radioisotopes and other antineoplastic therapeutic agents.

(Girentuximab, NCI Thesaurus)

Upon binding, CMD-193 is internalized, thereby delivering the attached calicheamicin to Lewis Y antigen-expressing tumor cells.

(Immunotoxin CMD-193, NCI Thesaurus)

Upon administration, anti-TF monoclonal antibody-MMAE conjugate binds to cell surface TF and is internalized.

(Anti-TF Monoclonal Antibody-MMAE Conjugate, NCI Thesaurus)

After binding to the EGF receptor, the agent is internalized by the cell, where the diphtheria toxin moiety exerts its cytotoxic effect, inhibiting protein synthesis through ADP-ribosylation of elongation factor 2.

(DAB389 Epidermal Growth Factor, NCI Thesaurus)

After binding to FR, the agent is internalized by tumor cells and the Tub-B-H moiety inhibits the polymerization of tubulin into microtubules.

(Folate Receptor-Targeted Tubulysin Conjugate EC1456, NCI Thesaurus)

Genetic disruption of the ability of neutrophils to kill internalized bacteria also impairs normal immune function, along with genetic or acquired lack of the normal number of neutrophils (neutropenia).

(Neutrophil Surface Molecule Pathway, NCI Thesaurus/BIOCARTA)

Upon administration, the monoclonal antibody moiety of DCDT2980S binds to B cell-specific CD22 receptors and is rapidly internalized, thereby delivering MMAE intracellularly.

(Anti-CD22 Monoclonal Antibody-MMAE Conjugate DCDT2980S, NCI Thesaurus)

The monoclonal antibody component recognizes and attaches to the membrane-associated antigen, dopamine-b-hydroxylase, resulting in the conjugate being internalized by receptor-mediated endocytosis.

(Anti-Dopamine-b-Hydroxylase Monoclonal Antibody-Saporin, NCI Thesaurus)