INSULIN

Pronunciation (US):

(GB):

IPA (US):

 Dictionary entry overview: What does insulin mean? 

• INSULIN (noun)
  The noun INSULIN has 1 sense:

1. hormone secreted by the isles of Langerhans in the pancreas; regulates storage of glycogen in the liver and accelerates oxidation of sugar in cells

  Familiarity information: INSULIN used as a noun is very rare.

 Dictionary entry details 

• INSULIN (noun)

Sense 1

Meaning:

Hormone secreted by the isles of Langerhans in the pancreas; regulates storage of glycogen in the liver and accelerates oxidation of sugar in cells

Classified under:

Nouns denoting body parts

Hypernyms ("insulin" is a kind of...):

endocrine; hormone; internal secretion (the secretion of an endocrine gland that is transmitted by the blood to the tissue on which it has a specific effect)

hypoglycaemic agent; hypoglycemic agent (any of various agents that decrease the level of glucose in the blood and are used in the treatment of diabetes mellitus)

Hyponyms (each of the following is a kind of "insulin"):

Lente Iletin; Lente Insulin (trade names for forms of insulin that are used to treat diabetes mellitus)

Humulin; recombinant human insulin (a form of insulin (trade name Humulin) made from recombinant DNA that is identical to human insulin; used to treat diabetics who are allergic to preparations made from beef or pork insulin)

 Context examples 

This allele, which encodes RAC-beta serine/threonine-protein kinase protein, is involved in mediation of cell survival and plays a putative role in the metabolic actions of insulin.

(AKT2 wt Allele, NCI Thesaurus)

ALK belongs to the insulin receptor superfamily and plays an important role in nervous system development.

(ALK Inhibitor CH5424802, NCI Thesaurus)

ALK belongs to the insulin receptor superfamily and plays an important role in nervous system development; its dysregulation and gene rearrangements are associated with a variety of tumors.

(ALK-FAK Inhibitor CEP-37440, NCI Thesaurus)

This allele, which encodes adiponectin protein, plays a role in the regulation of both lipid metabolism and insulin sensitivity.

(ADIPOQ wt Allele, NCI Thesaurus)

Obviously, the response is immediate; and despite the increased secretion of insulin, the amount of oxygen consumed by the cells does not change significantly as our study shows.

(Researchers Develop Insulin-Producing Cells Activated by Light for Diabetes, The Titi Tudorancea Bulletin)

Highly-expressed in a variety of tumor cell lines, human Oncogene ROS is a mutated variant of ROS1 Gene, which belongs to the sevenless subfamily of tyrosine kinase insulin receptor genes.

(Oncogene ROS, NCI Thesaurus)

Nonsulfonylurea insulin secretagogues and analogues of meglitinide with antihyperglycemic activity.

(Meglitinide Antidiabetic Agent, NCI Thesaurus)

PPAR-gamma is a member of this gene family that is activated by fatty acids and thiazolidinedione drugs that plays a role in insulin sensitivity and adipogenesis.

(Obesity and Thermogenesis Pathway, NCI Thesaurus/BIOCARTA)

IGF-1R, a receptor tyrosine kinase of the insulin receptor superfamily, and ErB3, a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases, are frequently overexpressed in solid tumors.

(Anti-ErbB3/Anti-IGF-1R Bispecific Monoclonal Antibody MM-141, NCI Thesaurus)

Activation of IGF-1R, a receptor tyrosine kinase of the insulin receptor superfamily overexpressed by various cancer cell types, stimulates cell proliferation, promotes angiogenesis, enables oncogenic transformation, and suppresses apoptosis.

(Anti-IGF-1R Monoclonal Antibody AVE1642, NCI Thesaurus)