English Dictionary |
INDINAVIR
Pronunciation (US): | (GB): |
Dictionary entry overview: What does indinavir mean?
• INDINAVIR (noun)
The noun INDINAVIR has 1 sense:
1. a protease inhibitor (trade name Crixivan) used for treating HIV
Familiarity information: INDINAVIR used as a noun is very rare.
Dictionary entry details
Sense 1
Meaning:
A protease inhibitor (trade name Crixivan) used for treating HIV
Classified under:
Nouns denoting man-made objects
Synonyms:
Crixivan; indinavir
Hypernyms ("indinavir" is a kind of...):
PI; protease inhibitor (an antiviral drug used against HIV; interrupts HIV replication by binding and blocking HIV protease; often used in combination with other drugs)
Context examples
Indinavir selectively binds to the active site of human immunodeficiency virus (HIV) protease and inhibits its activity, preventing the protease-mediated cleavage of gag-pol viral polyproteins; as a result immature, noninfectious virions are produced.
(Indinavir Sulfate, NCI Thesaurus)
An anhydrous formulation of indinavir, a synthetic hydroxyaminopentane amide agent that selectively inhibits the protease of both human immunodeficiency virus 1 and 2.
(Indinavir Anhydrous, NCI Thesaurus)
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