INACTIVATION

Pronunciation (US):

(GB):

IPA (US):

 Dictionary entry overview: What does inactivation mean? 

• INACTIVATION (noun)
  The noun INACTIVATION has 2 senses:

1. the process of rendering inactive

2. breaking up a military unit (by transfers or discharges)

  Familiarity information: INACTIVATION used as a noun is rare.

 Dictionary entry details 

• INACTIVATION (noun)

Sense 1

Meaning:

The process of rendering inactive

Classified under:

Nouns denoting natural processes

Context example:

thermal inactivation of serum samples

Hypernyms ("inactivation" is a kind of...):

action; activity; natural action; natural process (a process existing in or produced by nature (rather than by the intent of human beings))

Antonym:

activation (stimulation of activity in an organism or chemical)

Derivation:

inactivate (make inactive)

Sense 2

Meaning:

Breaking up a military unit (by transfers or discharges)

Classified under:

Nouns denoting acts or actions

Synonyms:

deactivation; inactivation

Hypernyms ("inactivation" is a kind of...):

discharge; dismissal; dismission; firing; liberation; release; sack; sacking (the termination of someone's employment (leaving them free to depart))

Domain category:

armed forces; armed services; military; military machine; war machine (the military forces of a nation)

Derivation:

inactivate (release from military service or remove from the active list of military service)

 Context examples 

Precise activation and inactivation of CDKs at specific points in the cell cycle are required for orderly cell division.

(Cell Cycle Pathway, NCI Thesaurus/KEGG)

Multiple endocrine neoplasia caused by inactivation of the tumor suppressor gene MEN-1.

(Multiple Endocrine Neoplasia Type 1, NCI Thesaurus)

Inactivation of PBPs interferes with the cross-linking of peptidoglycan chains necessary for bacterial cell wall strength and rigidity.

(Cefotaxime Sodium, NCI Thesaurus)

It is observed in patients with nevoid basal cell carcinoma syndrome and it is associated with PTCH gene inactivation.

(Nevoid Basal Cell Carcinoma Syndrome Associated Medulloblastoma, NCI Thesaurus)

This inactivation prevents the formation of the cross-linkage of peptidoglycan strands, thereby inhibiting the third and last stage of bacterial cell wall synthesis.

(Carbenicillin Indanyl Sodium, NCI Thesaurus)

Molecular mechanisms altered in NSCLC include activation of oncogenes, such as K-RAS and c-erbB-2, and inactivation of tumor suppressor genes, such as p53, p16INK4a, RAR-beta, and RASSF1.

(Non-Small Cell Lung Cancer Pathway, NCI Thesaurus/KEGG)

Inactivation of the vitamin D receptor induced diabetes and atherosclerosis, so normalizing vitamin D levels may have the opposite effect.

(How Vitamin D May Affect Heart Disease, Diabetes, NIH)

This gene is involved in the inactivation of peptide hormones.

(MME Gene, NCI Thesaurus)

This allele, which encodes cytochrome P450 26B1 protein, is involved in the specific inactivation of all-trans-retinoic acid.

(CYP26B1 wt Allele, NCI Thesaurus)

Mutational inactivation of XPG causes Cockayne syndrome, which is characterized by severe growth defects, mental retardation, and cachexia.

(DNA Excision Repair Protein ERCC-5, NCI Thesaurus)