IMMUNOSUPPRESSANT

Pronunciation (US):

(GB):

 Dictionary entry overview: What does immunosuppressant mean? 

• IMMUNOSUPPRESSANT (noun)
  The noun IMMUNOSUPPRESSANT has 1 sense:

1. a drug that lowers the body's normal immune response

  Familiarity information: IMMUNOSUPPRESSANT used as a noun is very rare.

 Dictionary entry details 

• IMMUNOSUPPRESSANT (noun)

Sense 1

Meaning:

A drug that lowers the body's normal immune response

Classified under:

Nouns denoting man-made objects

Synonyms:

immune suppressant drug; immunosuppressant; immunosuppressive; immunosuppressive drug; immunosuppressor

Hypernyms ("immunosuppressant" is a kind of...):

medicament; medication; medicinal drug; medicine ((medicine) something that treats or prevents or alleviates the symptoms of disease)

Hyponyms (each of the following is a kind of "immunosuppressant"):

mercaptopurine; Purinethol (a drug (trade name Purinethol) that interferes with the metabolism of purine and is used to treat acute lymphocytic leukemia)

amethopterin; methotrexate; methotrexate sodium (toxic antimetabolite that limits cellular reproduction by acting as an antagonist to folic acid; used to treat certain cancers and psoriasis and rheumatoid arthritis)

 Context examples 

Immunosuppressants may be used to keep a person from rejecting a bone marrow or organ transplant.

(Immunosuppressant, NCI Dictionary)

An antimetabolite and antifolate agent with antineoplastic and immunosuppressant activities.

(Methotrexate, NCI Thesaurus)

A derivative of the antitumor antibiotic spergualin with immunosuppressant activity.

(Gusperimus Trihydrochloride, NCI Thesaurus)

Encoded by human GLMN Gene, two alternative isoforms of ubiquitous monomeric Glomulin interact with immunophilins FKBP59, FKBPP52, and FKBP12 that bind the macrolide immunosuppressants FK506 and rapamycin.

(Glomulin, NCI Thesaurus)

A class of immunosuppressant binding proteins (immunophilins) specific for FK506 (tacrolimus) and rapamycin.

(FK506 Binding Protein, NCI Thesaurus)

Methotrexate also exhibits potent immunosuppressant properties.

(Methotrexate Sodium, NCI Thesaurus)

A 33-epi-chloro-derivative of the ascomycin macrolactam with immunosuppressant property.

(Pimecrolimus, NCI Thesaurus)

Phosphoramide mustards are also immunosuppressants, mutagens and teratogens.

(Phosphoramide Mustard, NCI Thesaurus)

These compounds are also powerful mutagens, teratogens, immunosuppressants, and carcinogens.

(Nitrogen Mustard Compound, NLM, Medical Subject Headings)

When bound to the immunophilin binding protein FKBP12, rapamycin inhibits mTOR kinase activity and has immunosuppressant activity.

(mTOR Signaling Pathway BioCarta, NCI Thesaurus/BIOCARTA)