IMMUNOGLOBULIN E

Pronunciation (US):

(GB):

 Dictionary entry overview: What does immunoglobulin E mean? 

• IMMUNOGLOBULIN E (noun)
  The noun IMMUNOGLOBULIN E has 1 sense:

1. one of the five major classes of immunoglobulins; present primarily in the skin and mucous membranes

  Familiarity information: IMMUNOGLOBULIN E used as a noun is very rare.

 Dictionary entry details 

• IMMUNOGLOBULIN E (noun)

Sense 1

Meaning:

One of the five major classes of immunoglobulins; present primarily in the skin and mucous membranes

Classified under:

Nouns denoting substances

Synonyms:

IgE; immunoglobulin E

Hypernyms ("immunoglobulin E" is a kind of...):

Ig; immune gamma globulin; immune globulin; immune serum globulin; immunoglobulin (a class of proteins produced in lymph tissue in vertebrates and that function as antibodies in the immune response)

Hyponyms (each of the following is a kind of "immunoglobulin E"):

reagin (an immunoglobulin E that is formed as an antibody against allergens (such as pollen); attaches to cell membranes causing the release of histamine and other substances responsible for the local inflammation characteristic of an allergy)

 Context examples 

The determination of the amount of immunoglobulin E present in a sample.

(Immunoglobulin E Measurement, NCI Thesaurus)

This gene plays a prominent role in immunoglobulin E production and cellular signal transduction.

(IL4R Gene, NCI Thesaurus)

The gene plays a role in the regulation of immunoglobulin E class switching.

(IL13 wt Allele, NCI Thesaurus)

It plays a major role in immunoglobulin E (IgE) production.

(Interleukin 4 Receptor, NCI Thesaurus)

A humanized monoclonal antibody directed against the C-epsilon 3 domain of immunoglobulin E. Olizumab binds to this IgE domain, thereby preventing IgE from binding to its high-affinity mast-cell receptor.

(Omalizumab, NCI Thesaurus)

This allele, which encodes interleukin-4 receptor alpha chain protein, plays a role in Th2 cell differentiation, immunoglobulin E (IgE) production and cellular proliferation regulation.

(IL4R wt Allele, NCI Thesaurus)

The scientists measured the amount of an antibody called sesame-specific immunoglobulin E (sIgE) in the blood of these 88 children.

(17% of Food-Allergic Children Have Sesame Allergy, National Institutes of Health)

Immediate hypersensitivity reaction - type I reaction, involves immunoglobulin E (IgE)-mediated release of chemical mediators from mast cells and basophils.

(Immediate Hypersensitivity, NCI Thesaurus)