IMMUNOGENIC

Pronunciation (US):

(GB):

 Dictionary entry overview: What does immunogenic mean? 

• IMMUNOGENIC (adjective)
  The adjective IMMUNOGENIC has 1 sense:

1. possessing the ability to elicit an immune response

  Familiarity information: IMMUNOGENIC used as an adjective is very rare.

 Dictionary entry details 

• IMMUNOGENIC (adjective)

Sense 1

Meaning:

Possessing the ability to elicit an immune response

Similar:

insusceptible; unsusceptible (not susceptible to)

Derivation:

immunogenicity (the property of eliciting an immune response)

 Context examples 

GM-CSF enhances the host immune response to poorly immunogenic tumors, possibly by activating T-cell and macrophage anti-tumor responses, and, so, decreasing tumor growth.

(GM-CSF DNA, NCI Thesaurus)

A plasmid DNA encoding an immunogenic peptide derived from the cancer-testis antigen NY-ESO-1 with potential immunostimulating and antitumor activities.

(NY-ESO-1 Plasmid DNA Cancer Vaccine, NCI Thesaurus)

FBP is a membrane-bound, tumor-associated antigen highly overexpressed in various tumor cell types, such as in breast, ovarian and endometrial cancers; E 39 is a strong immunogenic peptide.

(Folate Binding Protein E39 Peptide Vaccine, NCI Thesaurus)

A cancer vaccine consisting of an immunogenic peptide sequence from the cancer-testis antigen ESO-1, an antigen found in normal testis and various tumors, including melanoma, breast, bladder, prostate, and hepatocellular cancers.

(ESO-1 Peptide Vaccine, NCI Thesaurus)

A cancer vaccine consisting of an immunogenic peptide derived from the cancer-testis antigen (NY-ESO-1), an antigen found in normal testis and various tumors.

(NY-ESO-1 Peptide Vaccine, NCI Thesaurus)

A peptide-based melanoma cancer vaccine consisting of neoantigens and peptides derived from patient-specific melanoma immunogenic epitopes, combined with the immunostimulant poly-ICLC with potential immunomodulating and antineoplastic activities.

(Neoantigen-based Melanoma-Poly-ICLC Vaccine, NCI Thesaurus)

A peptide vaccine containing five immunogenic peptide epitopes of the human folate receptor alpha (FR alpha or FOLR1), including FR30, FR56, FR76, FR113, and FR238, with potential immunomodulating and antineoplastic activity.

(Multi-epitope Folate Receptor Alpha Peptide Vaccine, NCI Thesaurus)

A vaccine consisting of recombinant adenovirus vector encoding MART-1 (melanoma antigen recognized by T-cells 1), an immunogenic protein of unknown function that is expressed by certain types of melanoma.

(MART-1 Adenovirus Vaccine, NCI Thesaurus)

Keyhole limpet hemocyanin is an immunogenic carrier protein that, in vivo, increases antigenic immune responses to haptens and other weak antigens such as idiotype proteins.

(Keyhole limpet hemocyanin, NCI Thesaurus)

The limited expression of Ep-CAM in normal epithelial tissues and immunogenic MHC class I and II restricted epitopes identified on Ep-CAM, provide opportunities for developing effective multiepitope cancer vaccines targeting Ep-CAM.

(Ep-CAM, NCI Thesaurus)