IGE

Pronunciation (US):

(GB):

IPA (US):

 Dictionary entry overview: What does IgE mean? 

• IGE (noun)
  The noun IGE has 1 sense:

1. one of the five major classes of immunoglobulins; present primarily in the skin and mucous membranes

  Familiarity information: IGE used as a noun is very rare.

 Dictionary entry details 

• IGE (noun)

Sense 1

Meaning:

One of the five major classes of immunoglobulins; present primarily in the skin and mucous membranes

Classified under:

Nouns denoting substances

Synonyms:

IgE; immunoglobulin E

Hypernyms ("IgE" is a kind of...):

Ig; immune gamma globulin; immune globulin; immune serum globulin; immunoglobulin (a class of proteins produced in lymph tissue in vertebrates and that function as antibodies in the immune response)

Hyponyms (each of the following is a kind of "IgE"):

reagin (an immunoglobulin E that is formed as an antibody against allergens (such as pollen); attaches to cell membranes causing the release of histamine and other substances responsible for the local inflammation characteristic of an allergy)

 Context examples 

This allele, which encodes interleukin-4 receptor alpha chain protein, plays a role in Th2 cell differentiation, immunoglobulin E (IgE) production and cellular proliferation regulation.

(IL4R wt Allele, NCI Thesaurus)

Reexposure to the antigen can then result in the antigen binding to and cross-linking the bound IgE antibodies on the mast cells and basophils.

(Immediate Hypersensitivity, NCI Thesaurus)

A measurement of the human anti-sheep IgE antibodies in a biological specimen.

(Human Anti-Sheep IgE Antibody Measurement, NCI Thesaurus/CDISC)

The determination of the amount of human anti-sheep IgE antibody present in a sample.

(Human Anti-Sheep IgE Antibody Measurement, NCI Thesaurus)

This allele, which encodes low affinity immunoglobulin epsilon Fc receptor protein, plays a role in both the regulation of IgE production and the differentiation of B cells.

(FCER2 wt Allele, NCI Thesaurus)

Omalizumab blocks the activity of IgE, an immune system molecule central to the allergic response.

(Omalizumab improves efficacy of oral immunotherapy for multiple food allergies, National Institutes of Health)

Though the exact mechanism is not clear, the therapy results in an increase in serum levels of allergen-specific IgG, suppression of specific IgE, and an increase in suppressor T-cell activity.

(Immunologic Desensitization, NLM, Medical Subject Headings)

It plays a major role in immunoglobulin E (IgE) production.

(Interleukin 4 Receptor, NCI Thesaurus)

This protein is involved in B cell differentiation and IgE production.

(Low Affinity Immunoglobulin Epsilon Fc Receptor, NCI Thesaurus)

The heavy chain of the immunoglobulin, IgE, is defective.

(Multiple Myeloma-IgE, NCI Thesaurus)