IG

Pronunciation (US):

(GB):

 Dictionary entry overview: What does Ig mean? 

• IG (noun)
  The noun IG has 1 sense:

1. a class of proteins produced in lymph tissue in vertebrates and that function as antibodies in the immune response

  Familiarity information: IG used as a noun is very rare.

 Dictionary entry details 

• IG (noun)

Sense 1

Meaning:

A class of proteins produced in lymph tissue in vertebrates and that function as antibodies in the immune response

Classified under:

Nouns denoting substances

Synonyms:

Ig; immune gamma globulin; immune globulin; immune serum globulin; immunoglobulin

Hypernyms ("Ig" is a kind of...):

gamma globulin; human gamma globulin (a plasma protein containing the immunoglobulins that are responsible for immune responses)

antibody (any of a large variety of proteins normally present in the body or produced in response to an antigen which it neutralizes, thus producing an immune response)

Hyponyms (each of the following is a kind of "Ig"):

IgA; immunoglobulin A (one of the most common of the five major classes of immunoglobulins; the chief antibody in the membranes of the gastrointestinal and respiratory tracts)

IgD; immunoglobulin D (one of the five major classes of immunoglobulins; present in blood serum in small amounts)

IgE; immunoglobulin E (one of the five major classes of immunoglobulins; present primarily in the skin and mucous membranes)

IgG; immunoglobulin G (one of the five major classes of immunoglobulins; the main antibody defense against bacteria)

IgM; immunoglobulin M (one of the five major classes of immunoglobulins; involved in fighting blood infections and in triggering production of immunoglobulin G)

tetanus immune globulin; tetanus immunoglobulin (sterile solution of globulins derived from the blood plasma of a person who has been immunized for tetanus; provides short-term immunization against tetanus in cases of possible exposure to the tetanus bacillus)

 Context examples 

CD8 Antigen Beta Polypeptide 1 glycoprotein exhibits significant homology to Ig variable light chains and mediates efficient cell-cell interactions in the immune system, as an alpha/alpha or alpha/beta coreceptor with T-cell receptor.

(CD8 Antigen, Beta Polypeptide 1, NCI Thesaurus)

Neural Cell Adhesion Molecule is a membrane-bound glycoprotein member of the Ig superfamily that binds to a variety of other cell adhesion proteins involved in diverse contact-mediated interactions.

(CD56 Antigen, NCI Thesaurus)

A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with tumor-derived clonal immunoglobulin (Ig) with potential immunostimulatory and antineoplastic activities.

(Idiotype-Pulsed Autologous Dendritic Cell Vaccine APC8020, NCI Thesaurus)

NBS1/gamma-H2AX facilitate AID-dependent DNA break repair in G1 cells undergoing Ig heavy-chain constant region class switch recombination.

(Histone H2AX, NCI Thesaurus)

This agent is prepared by fusing murine immunoglobulin (Ig) light and heavy variable regions derived from the murine IgG3 antibody KM-641 to a human constant (Fc) region.

(Ecromeximab, NCI Thesaurus)

A proprietary, allogeneic tumor cell vaccine expressing a recombinant secretory form of the heat shock protein gp96 fusion (gp96-Ig) with potential antineoplastic activity.

(Gp96-Ig-secreting Allogeneic Tumor-Cell Vaccine HS110, NCI Thesaurus)

This signalling ultimately results in the expression of immediate early genes that further activate the expression of other genes involved in B cell proliferation, differentiation and Ig production as well as other processes.

(B Cell Receptor Signaling Pathway, NCI Thesaurus/KEGG)

As antibodies that occur naturally due to sensitization to alpha-Gal present on symbiotic bacterial flora, anti-alpha-Gal Igs are present in unusually high amounts in human sera.

(Alpha-Gal Glycosphingolipids, NCI Thesaurus)

Ig Class switch DNA recombination recruits NBS1/gamma-H2AX in G1.

(Nibrin, NCI Thesaurus)

Vaccination with myeloma Ig Id-KLH conjugate vaccine may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against myeloma cells, resulting in decreased tumor growth.

(Myeloma Ig Id-KLH Conjugate Vaccine, NCI Thesaurus)