IA

Pronunciation (US):

(GB):

IPA (US):

 Dictionary entry overview: What does IA mean? 

• IA (noun)
  The noun IA has 1 sense:

1. a state in midwestern United States

  Familiarity information: IA used as a noun is very rare.

 Dictionary entry details 

• IA (noun)

Sense 1

Meaning:

A state in midwestern United States

Classified under:

Nouns denoting spatial position

Synonyms:

Hawkeye State; IA; Ia.; Iowa

Instance hypernyms:

American state (one of the 50 states of the United States)

Meronyms (parts of "IA"):

Davenport (a city in eastern Iowa on the Mississippi River across from Moline and Rock Island)

Cedar Rapids (a city in eastern Iowa)

Clinton (a town in east central Iowa)

capital of Iowa; Des Moines (the capital and largest city in Iowa)

Dubuque (a town in eastern Iowa on the Mississippi River)

Mason City (a town in north central Iowa)

Ottumwa (a town in southeast Iowa)

Sioux City (a city in northeastern Iowa where the Big Sioux River joins the Missouri)

Little Sioux River (a river that rises in southwestern Minnesota and flows southwestward to the Missouri River in western Iowa)

Holonyms ("IA" is a part of...):

Corn Belt (the midwestern states in the U.S. where corn is grown; Iowa and Illinois are excellent for raising corn and corn-fed livestock)

middle west; Midwest; midwestern United States (the north central region of the United States (sometimes called the heartland or the breadbasket of America))

America; the States; U.S.; U.S.A.; United States; United States of America; US; USA (North American republic containing 50 states - 48 conterminous states in North America plus Alaska in northwest North America and the Hawaiian Islands in the Pacific Ocean; achieved independence in 1776)

 Context examples 

This allele, which encodes insulin-like growth factor IA protein, is involved in the mediation of peptides that exert growth-promoting effects involved in mammalian growth and development.

(IGF1 wt Allele, NCI Thesaurus)

This allele, which encodes bone morphogenetic protein receptor type IA protein, is involved in signal transduction pertaining to bone morphogenesis.

(BMPR1A wt Allele, NCI Thesaurus)

A highly selective, potent, and orally bioavailable small molecule inhibitor of the delta isoform of the 110 kDa catalytic subunit of class IA phosphoinositide-3 kinases (PI3K) with potential immunomodulating and antineoplastic activities.

(PI3K-delta Inhibitor AMG 319, NCI Thesaurus)

A class IA anti-arrhythmic agent with cardiac depressant property.

(Disopyramide, NCI Thesaurus)

An inhibitor of the beta and delta isoforms of the 110 kDa catalytic subunit of class IA phosphoinositide-3 kinases (PI3K) with potential immunomodulating and antineoplastic activities. p110beta/delta PI3K inhibitor GS-9820 inhibits the activity of PI3K, thereby preventing the production of the second messenger phosphatidylinositol-3,4,5-trisphosphate (PIP3), which decreases tumor cell proliferation and induces cell death.

(p110beta/delta PI3K Inhibitor GS-9820, NCI Thesaurus)

For cervical cancer, it refers to invasive cancer that is confined to the cervix; for endometrial cancer, it refers to cancer confined to the corpus uteri with no or less than one-half myometrial invasion (IA) or invasion of one-half or more of the myometrium (IB).

(FIGO Stage I, NCI Thesaurus)

Receptors for BMPs, members of the transforming growth factor-beta (TGFb) superfamily, are persistently expressed during cardiac development, yet mice lacking type II or type IA BMP receptors die at gastrulation and cannot be used to assess potential later roles in creation of the heart.

(ALK Pathway, NCI Thesaurus/BIOCARTA)