HYDROXYZINE

Pronunciation (US):

(GB):

 Dictionary entry overview: What does hydroxyzine mean? 

• HYDROXYZINE (noun)
  The noun HYDROXYZINE has 1 sense:

1. a drug (trade names Atarax and Vistaril) used as a tranquilizer to treat anxiety and motion sickness

  Familiarity information: HYDROXYZINE used as a noun is very rare.

 Dictionary entry details 

• HYDROXYZINE (noun)

Sense 1

Meaning:

A drug (trade names Atarax and Vistaril) used as a tranquilizer to treat anxiety and motion sickness

Classified under:

Nouns denoting man-made objects

Synonyms:

Atarax; hydroxyzine; hydroxyzine hydrochloride; Vistaril

Hypernyms ("hydroxyzine" is a kind of...):

antianxiety drug; anxiolytic; anxiolytic drug; minor tranquilizer; minor tranquilliser; minor tranquillizer (a tranquilizer used to relieve anxiety and reduce tension and irritability)

 Context examples 

Cetirizine is a metabolite of hydroxyzine and a selective peripheral histamine H1-receptor antagonist.

(Cetirizine, NCI Thesaurus)

Hydroxyzine's antihistaminic effect is due to its metabolite, cetirizine, a potent H1 receptor antagonist and selective inhibitor of peripheral H1 receptors.

(Hydroxyzine, NCI Thesaurus)

A synthetic phenylmethyl-piperazinyl derivative, antihistaminic Cetirizine is a metabolite of hydroxyzine and a selective peripheral histamine H1-receptor antagonist.

(Cetirizine Hydrochloride, NCI Thesaurus)

In addition, hydroxyzine pamoate crosses the blood-brain barrier and acts on the histamine H1-receptors in the central nervous system.

(Hydroxyzine Pamoate, NCI Thesaurus)

In addition, hydroxyzine hydrochloride crosses the blood-brain barrier and acts on the histamine H1-receptors in the central nervous system.

(Hydroxyzine Hydrochloride, NCI Thesaurus)

The sedative properties of hydroxyzine occur as a result of suppression of certain subcortical regions of the brain.

(Hydroxyzine, NCI Thesaurus)

The pamoate salt form of hydroxyzine, a synthetic piperazine histamine H1-receptor antagonist with anti-allergic, antispasmodic, sedative, anti-emetic and anti-anxiety properties.

(Hydroxyzine Pamoate, NCI Thesaurus)

The hydrochloride salt form of hydroxyzine, a piperazine histamine H1-receptor antagonist with anti-allergic, antispasmodic, sedative, anti-emetic and anti-anxiety properties.

(Hydroxyzine Hydrochloride, NCI Thesaurus)

Secondary to its central anticholinergic actions, hydroxyzine may be effective as an antiemetic.

(Hydroxyzine, NCI Thesaurus)

Hydroxyzine pamoate blocks the H1 histamine receptor and prevents the symptoms that are caused by histamine activity on capillaries, bronchial smooth muscle, and gastrointestinal smooth muscle, including vasodilatation, increased capillary permeability, bronchoconstriction, and spasmodic contraction of gastrointestinal smooth muscle.

(Hydroxyzine Pamoate, NCI Thesaurus)