English Dictionary

HYDRALAZINE

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 Dictionary entry overview: What does hydralazine mean? 

HYDRALAZINE (noun)
  The noun HYDRALAZINE has 1 sense:

1. an antihypertensive drug (trade name Apresoline) that dilates blood vessels; used (often with a diuretic) to treat hypertension and congestive heart failureplay

  Familiarity information: HYDRALAZINE used as a noun is very rare.


 Dictionary entry details 


HYDRALAZINE (noun)


Sense 1

Meaning:

An antihypertensive drug (trade name Apresoline) that dilates blood vessels; used (often with a diuretic) to treat hypertension and congestive heart failure

Classified under:

Nouns denoting man-made objects

Synonyms:

Apresoline; hydralazine

Hypernyms ("hydralazine" is a kind of...):

antihypertensive; antihypertensive drug (a drug that reduces high blood pressure)

vasodilative; vasodilator (a drug that causes dilation of blood vessels)


 Context examples 


A hydralazine and monoamine oxidase (MAO) inhibitor with antidepressant activity.

(Isocarboxazid, NCI Thesaurus)

In addition to its cardiovascular effects, hydralazine inhibits DNA methyltransferase, which may result in inhibition of DNA methylation in tumor cells.

(Hydralazine Hydrochloride, NCI Thesaurus)

Hydralazine exerts its vasodilatory effects through modification of the contractile state of arterial vascular smooth muscle by altering intracellular calcium release, and interfering with smooth muscle cell calcium influx.

(Hydralazine, NCI Thesaurus)

Hydralazine alters intracellular calcium release and interferes with smooth muscle cell calcium influx, resulting in arterial vasodilatation.

(Hydralazine Hydrochloride, NCI Thesaurus)

The hydrochloride salt of hydralazine, a phthalazine derivative with antihypertensive and potential antineoplastic activities.

(Hydralazine Hydrochloride, NCI Thesaurus)



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