HYBRIDOMA

Pronunciation (US):

(GB):

 Dictionary entry overview: What does hybridoma mean? 

• HYBRIDOMA (noun)
  The noun HYBRIDOMA has 1 sense:

1. a hybrid cell resulting from the fusion of a lymphocyte and a tumor cell; used to culture a specific monoclonal antibody

  Familiarity information: HYBRIDOMA used as a noun is very rare.

 Dictionary entry details 

• HYBRIDOMA (noun)

Sense 1

Meaning:

A hybrid cell resulting from the fusion of a lymphocyte and a tumor cell; used to culture a specific monoclonal antibody

Classified under:

Nouns denoting body parts

Hypernyms ("hybridoma" is a kind of...):

somatic cell; vegetative cell (any of the cells of a plant or animal except the reproductive cells; a cell that does not participate in the production of gametes)

 Context examples 

Hybridomas of mouse myeloma cells and mouse spleen cells immunized with human melanoma cell were produced, of which one secreted MoAb 8.2.

(Monoclonal Antibody 8.2, NCI Thesaurus)

Produced by T-cells, monocytes, fibroblasts, and many other cells, Interleukin 6 stimulates the growth of hybridomas and plasmacytomas, as well as the growth and differentiation of B-cells.

(Interleukin-6, NCI Thesaurus)

Hybridomas of mouse myeloma cells and mouse spleen cells immunized with human melanoma cell were produced, of which one secreted MoAb 96.5.

(Monoclonal Antibody 96.5, NCI Thesaurus)

A bispecific antibody containing a 4G7 hybridoma secreting IgG1 antibody specific for B-lymphocytes and a monoclonal antibody targeting Fc gamma RI-expressing cells.

(Bispecific Antibody 4G7xH22, NCI Thesaurus)

Hybridoma cells are cloned to establish cell lines producing a specific antibody that is chemically and immunologically homogeneous.

(Monoclonal antibody, NCI Thesaurus)

Hybridomas of SP2/0 mouse myeloma cells and mouse spleen cells are immunized with cultured human melanoma cells, and subsequently one of the hybridomas secreted MoAb 48.7.

(Monoclonal Antibody 48.7, NCI Thesaurus)

A synthetic antibody produced by a genetically homogenous population of hybrid cells (hybridoma) against determinant idiotypes (Id) which usually mimic human epitopes.

(Anti-Idiotype Specified Monoclonal Antibody, NCI Thesaurus)

An antibody produced by a clone or genetically homogenous fast-growing cells i.e., hybridoma.

(Monoclonal antibody, NCI Thesaurus)

Interleukin-6 (IL-6), a glycoprotein produced by activated T-cells and a variety of other cells, induces the production of IgM by B-cells and can be used to replace feeder cells for the growth and maintenance of B-cell hybridomas in vitro.

(Interleukin-6, NCI Thesaurus)