HYBRIDIZE

Pronunciation (US):

(GB):

IPA (US):

 Dictionary entry overview: What does hybridize mean? 

• HYBRIDIZE (verb)
  The verb HYBRIDIZE has 1 sense:

1. breed animals or plants using parents of different races and varieties

  Familiarity information: HYBRIDIZE used as a verb is very rare.

 Dictionary entry details 

• HYBRIDIZE (verb)

Present simple: I / you / we / they hybridize    ... he / she / it hybridizes   
Past simple: hybridized   
Past participle: hybridized   
-ing form: hybridizing   

Sense 1

Meaning:

Breed animals or plants using parents of different races and varieties

Classified under:

Verbs of touching, hitting, tying, digging

Synonyms:

cross; crossbreed; hybridise; hybridize; interbreed

Context example:

these species do not interbreed

Hypernyms (to "hybridize" is one way to...):

breed (cause to procreate (animals))

Troponyms (each of the following is one way to "hybridize"):

backcross (mate a hybrid of the first generation with one of its parents)

Sentence frame:

Somebody ----s something

Derivation:

hybrid ((genetics) an organism that is the offspring of genetically dissimilar parents or stock; especially offspring produced by breeding plants or animals of different varieties or breeds or species)

hybrid (a composite of mixed origin)

hybridization; hybridizing ((genetics) the act of mixing different species or varieties of animals or plants and thus to produce hybrids)

 Context examples 

Functioning as an anti-sense agent, it hybridizes to the translation initiation region of the human mRNA for the oncogene H-Ras.

(ISIS 2503, NCI Thesaurus)

A synthetic, 20-base antisense oligodeoxynucleotide that hybridizes to c-raf kinase messenger RNA.

(ISIS 5132, NCI Thesaurus)

That's the news from a study out of Lehigh University, the first to document naturally hybridizing songbirds' preference for the smell of their own species.

(Scent brings songbirds to the yard, National Science Foundation)

Wild-type molecules are rendered inactive for amplification by binding of a peptide nucleic acid (PNA) probe that hybridizes to wild-type sequence with greater affinity and under less stringent conditions.

(Peptide Nucleic Acid Clamping, NCI Thesaurus)

As an antisense molecule, ISIS 3521 hybridizes to the 3-untranslated region of the human protein kinase C (PKC-alpha) mRNA, thereby inhibiting PKC-alpha expression and growth of PKC-alpha-dependent tumor cells.

(ISIS 3521, NCI Thesaurus)

Oligonucleotide LY2181308 hybridizes to survivin mRNA, thereby blocking translation of survivin protein, a member of the inhibitor of apoptosis (IAP) family.

(Gataparsen Sodium, NCI Thesaurus)

Briefly, sequence-specific probes are hybridized to cells fixed on slides and the sequestered probe is visualized by a peroxidase reaction.

(Chromogenic In Situ Hybridization, NCI Thesaurus)

Upon internalization, EphA2-targeting DOPC-encapsulated siRNA can hybridize to EphA2 DNA and mRNA, thereby interfering with both the transcription and translation of EphA2, and thus inhibiting tumor cell growth.

(EphA2-targeting DOPC-encapsulated siRNA, NCI Thesaurus)

EL625 hybridizes with p53 mRNA molecules, and induces Rnase H dependent hydrolysis of p53 transcripts in the double stranded section of the hybrids, thereby resulting in loss of p53 production.

(EL625, NCI Thesaurus)

Complementary DNA (cDNA) clone inserts robotically printed onto a glass slide and subsequently hybridized to two differentially fluorescently labeled probes.

(cDNA Microarray Analysis, NCI Thesaurus)