HUNTINGTON'S DISEASE

Pronunciation (US):

(GB):

IPA (US):

 Dictionary entry overview: What does Huntington's disease mean? 

• HUNTINGTON'S DISEASE (noun)
  The noun HUNTINGTON'S DISEASE has 1 sense:

1. hereditary disease; develops in adulthood and ends in dementia

  Familiarity information: HUNTINGTON'S DISEASE used as a noun is very rare.

 Dictionary entry details 

• HUNTINGTON'S DISEASE (noun)

Sense 1

Meaning:

Hereditary disease; develops in adulthood and ends in dementia

Classified under:

Nouns denoting stable states of affairs

Synonyms:

Huntington's chorea; Huntington's disease

Hypernyms ("Huntington's disease" is a kind of...):

monogenic disease; monogenic disorder (an inherited disease controlled by a single pair of genes)

chorea (any of several degenerative nervous disorders characterized by spasmodic movements of the body and limbs)

autosomal dominant disease; autosomal dominant disorder (a disease caused by a dominant mutant gene on an autosome)

 Context examples 

It is seen in patients with Huntington's disease.

(Chorea, NCI Thesaurus)

There are a few hypotheses for the connection between these aggregates and the neurodegeneration observed in Huntington's disease.

(Inhibition of Huntington's Disease Pathway, NCI Thesaurus/BIOCARTA)

Alteration in the expression of this gene is associated with the development of Huntington's disease.

(MIR132 wt Allele, NCI Thesaurus)

While it has no known role in oncogenesis, MIR132 plays a role in the development of Huntington's disease.

(MIR132 Gene, NCI Thesaurus)

If one of your parents has Huntington's disease, you have a 50 percent chance of getting it.

(Huntington's Disease, NIH: National Institute of Neurological Disorders and Stroke)

Degenerative nerve diseases include: • Alzheimer's disease • Amyotrophic lateral sclerosis • Friedreich's ataxia • Huntington's disease • Lewy body disease • Parkinson's disease • Spinal muscular atrophy

(Degenerative Nerve Diseases, NIH)

Major types include: • Diseases caused by faulty genes, such as Huntington's disease and muscular dystrophy • Problems with the way the nervous system develops, such as spina bifida • Degenerative diseases, where nerve cells are damaged or die, such as Parkinson's diseaseand Alzheimer's disease • Diseases of the blood vessels that supply the brain, such as stroke • Injuries to the spinal cord and brain • Seizure disorders, such as epilepsy • Cancer, such as brain tumors • infections, such as meningitis

(Neurologic Diseases, NIH)

Huntington's disease is a neurodegenerative condition caused by a dominant mutation in a gene encoding a protein now called huntingtin.

(Inhibition of Huntington's Disease Pathway, NCI Thesaurus/BIOCARTA)

Huntington's disease (HD) is an inherited disease that causes certain nerve cells in the brain to waste away.

(Huntington's Disease, NIH: National Institute of Neurological Disorders and Stroke)