HOMOZYGOUS

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 Dictionary entry overview: What does homozygous mean? 

• HOMOZYGOUS (adjective)
  The adjective HOMOZYGOUS has 1 sense:

1. having identical alleles at corresponding chromosomal loci

  Familiarity information: HOMOZYGOUS used as an adjective is very rare.

 Dictionary entry details 

• HOMOZYGOUS (adjective)

Sense 1

Meaning:

Having identical alleles at corresponding chromosomal loci

Context example:

these two fruit flies are homozygous for red eye color

Domain category:

genetic science; genetics (the branch of biology that studies heredity and variation in organisms)

Antonym:

heterozygous (having dissimilar alleles at corresponding chromosomal loci)

Derivation:

homozygosity (the state of being homozygous; having two identical alleles of the same gene)

 Context examples 

Duodenal expression of multidrug resistance protein 1 is also significantly reduced in individuals that have a homozygous phenotype for this allele.

(ABCB1 2 Allele, NCI Thesaurus)

A person may be homozygous for the normal allele or for a mutation.

(Homozygosity, NCI Dictionary)

A quantitative measurement of the amount of homozygous B-type creatine kinase present in a sample.

(Creatine Kinase BB Measurement, NCI Thesaurus)

A measurement of the homozygous B-type creatine kinase in a biological specimen.

(Creatine Kinase BB Measurement, NCI Thesaurus/CDISC)

Homozygous BAP1 intragenic rearrangements and allelic deletions occur in lung carcinoma.

(BAP1 wt Allele, NCI Thesaurus)

Studies with homozygous knockout mice have suggested that stem cell factor (SCF or KITLG), c-Kit, microphthalmia (Mitf), and B-cell CLL/lymphoma 2 (Bcl2) genes regulate melanocytic development.

(Melanocyte Development Pathway, NCI Thesaurus/BIOCARTA)

A measurement of the homozygous M-type creatine kinase in a biological specimen.

(Creatine Kinase MM Measurement, NCI Thesaurus/CDISC)

A quantitative measurement of the amount of homozygous M-type creatine kinase present in a sample.

(Creatine Kinase MM Measurement, NCI Thesaurus)

A partial congenic mouse with background strain of C57BL/6 and 129/Sv chimera, containing a heterozygous or homozygous p53 mutation.

(B6.129-Trp53tm1Brd N5, NCI Thesaurus)

Autosomal recessive inheritance refers to genetic conditions that occur only when mutations are present in both copies of a given gene (i.e., the person is homozygous for a mutation, or carries two different mutations of the same gene, a state referred to as compound heterozygosity).

(Autosomal Recessive Inheritance, NCI Dictionary)