HODGKIN'S DISEASE

Pronunciation (US):

(GB):

IPA (US):

 Dictionary entry overview: What does Hodgkin's disease mean? 

• HODGKIN'S DISEASE (noun)
  The noun HODGKIN'S DISEASE has 1 sense:

1. a malignant disorder in which there is progressive (but painless) enlargement of lymph tissue followed by enlargement of the spleen and liver

  Familiarity information: HODGKIN'S DISEASE used as a noun is very rare.

 Dictionary entry details 

• HODGKIN'S DISEASE (noun)

Sense 1

Meaning:

A malignant disorder in which there is progressive (but painless) enlargement of lymph tissue followed by enlargement of the spleen and liver

Classified under:

Nouns denoting stable states of affairs

Hypernyms ("Hodgkin's disease" is a kind of...):

lymphoma (a neoplasm of lymph tissue that is usually malignant; one of the four major types of cancer)

 Context examples 

CD30 is over-expressed in various lymphoproliferative disorders, Hodgkin's disease and other lymphomas, and other cancers.

(Iratumumab, NCI Thesaurus)

A lymphoma, previously known as Hodgkin's disease, characterized by the presence of Reed-Sternberg cells.

(Hodgkin lymphoma, NCI Thesaurus)

This gene is aberrantly expressed in Reed-Sternberg cells of Hodgkin's disease.

(CLIP1 wt Allele, NCI Thesaurus)

CD30, a member of the tumor necrosis factor (TNF) receptor superfamily, is expressed on activated lymphocytes transiently and is constitutively expressed in hematologic malignancies including Hodgkin's disease and some T-cell non-Hodgkin's lymphomas.

(Anti-CD30 Monoclonal Antibody MDX-1401, NCI Thesaurus)

LMP-2, an EBV transmembrane protein, is expressed in various malignancies including nasopharyngeal cancer and EBV-positive Hodgkin's disease.

(LMP-2:340-349 Peptide Vaccine, NCI Thesaurus)

EBV, a ubiquitous human herpes virus, is associated with various malignancies, including nasopharyngeal carcinoma, Hodgkin's disease, non-Hodgkin's lymphoma, and other lymphomas.

(Allogeneic Epstein-Barr Virus-Specific Cytotoxic T-Lymphocytes, NCI Thesaurus)

The CD40 receptor, a member of the tumor necrosis factor (TNF) receptor super-family, is highly expressed on most B lineage hematologic malignancies including multiple myeloma, non-Hodgkin's lymphoma, chronic lymphocytic leukemia, Hodgkin's disease and acute lymphoblastic leukemia.

(Dacetuzumab, NCI Thesaurus)