HMG-COA REDUCTASE

Pronunciation (US):

(GB):

 Dictionary entry overview: What does HMG-CoA reductase mean? 

• HMG-COA REDUCTASE (noun)
  The noun HMG-COA REDUCTASE has 1 sense:

1. a liver enzyme that is responsible for producing cholesterol

  Familiarity information: HMG-COA REDUCTASE used as a noun is very rare.

 Dictionary entry details 

• HMG-COA REDUCTASE (noun)

Sense 1

Meaning:

A liver enzyme that is responsible for producing cholesterol

Classified under:

Nouns denoting substances

Synonyms:

5-hydroxy-3-methylglutaryl-coenzyme A reductase; HMG-CoA reductase

Hypernyms ("HMG-CoA reductase" is a kind of...):

reductase (an enzyme that catalyses the biochemical reduction of some specified substance)

 Context examples 

An HMG-CoA reductase inhibitor that was initially isolated from the mold Pythium ultimum.

(Mevastatin, NCI Thesaurus)

An inhibitor of squalene synthase, an enzyme downstream of HMG-CoA reductase in the synthesis of cholesterol.

(Lapaquistat, NCI Thesaurus)

Lovastatin is a type of HMG-CoA reductase inhibitor (statin).

(Lovastatin, NCI Dictionary)

It is a type of HMG-CoA reductase inhibitor and a type of statin.

(Atorvastatin, NCI Dictionary)

Inhibition of HMG-CoA reductase acts to lower plasma cholesterol and lipoprotein levels.

(HMG-CoA reductase inhibitor, NCI Thesaurus)

HMG-CoA reductase inhibitor drugs are called statins.

(HMG-CoA reductase inhibitor, NCI Dictionary)

Mevacor is a type of HMG-CoA reductase inhibitor (statin).

(Mevacor, NCI Dictionary)

Compounds that inhibit HMG-CoA reductases.

(HMG-CoA reductase inhibitor, NLM, Medical Subject Headings)

Also called HMG-CoA reductase inhibitor.

(hydroxymethylglutaryl-coenzyme A reductase inhibitor, NCI Dictionary)

Any substance that inhibits HMG-CoA reductase, a key enzyme in cholesterol synthesis.

(HMG-CoA reductase inhibitor, NCI Thesaurus)