HETEROZYGOUS

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 Dictionary entry overview: What does heterozygous mean? 

• HETEROZYGOUS (adjective)
  The adjective HETEROZYGOUS has 1 sense:

1. having dissimilar alleles at corresponding chromosomal loci

  Familiarity information: HETEROZYGOUS used as an adjective is very rare.

 Dictionary entry details 

• HETEROZYGOUS (adjective)

Sense 1

Meaning:

Having dissimilar alleles at corresponding chromosomal loci

Context example:

heterozygous for eye color

Domain category:

genetic science; genetics (the branch of biology that studies heredity and variation in organisms)

Antonym:

homozygous (having identical alleles at corresponding chromosomal loci)

Derivation:

heterozygosity (the state of being heterozygous; having two different alleles of the same gene)

 Context examples 

Heterozygous deletion of the FZD3 gene may contribute to the Williams syndrome phenotype.

(Frizzled 9, NCI Thesaurus)

Heterozygous loss-of-function mutations in the gene are associated with the blood group-Lutheran inhibitor phenotype.

(KLF1 wt Allele, NCI Thesaurus)

It is detected when heterozygous markers for a locus appear monomorphic because one of the alleles was deleted.

(Loss of Heterozygosity, NLM, Medical Subject Headings)

A measurement of the heterozygous MB-type creatine kinase in a biological specimen.

(Creatine Kinase MB Measurement, NCI Thesaurus/CDISC)

Individuals who are heterozygous for this allele display a poor metabolizer phenotype.

(CYP2C19*4 Allele, NCI Thesaurus)

A quantitative measurement of the amount of heterozygous MB-type creatine kinase present in a sample.

(Creatine Kinase MB Measurement, NCI Thesaurus)

A partial congenic mouse with background strain of C57BL/6 and 129/Sv chimera, containing a heterozygous or homozygous p53 mutation.

(B6.129-Trp53tm1Brd N5, NCI Thesaurus)

A heterozygous state in which a person has a mutation in a beta globin allele causing beta thalassemia, together with other structural variants in the other allele.

(Beta Thalassemia Plus Structural Variants, NCI Thesaurus)

A condition in which a person is heterozygous for a globin gene, with a one normal allele and one defective allele.

(Hemoglobin Trait, NCI Thesaurus)

Autosomal dominant inheritance refers to genetic conditions that occur when a mutation is present in one copy of a given gene (i.e., the person is heterozygous).

(Autosomal Dominant Inheritance, NCI Dictionary)