HERPES SIMPLEX

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 Dictionary entry overview: What does herpes simplex mean? 

• HERPES SIMPLEX (noun)
  The noun HERPES SIMPLEX has 2 senses:

1. an infection caused by the herpes simplex virus; affects the skin and nervous system; produces small temporary (but sometimes painful) blisters on the skin and mucous membranes

2. a herpes virus that affects the skin and nervous system

  Familiarity information: HERPES SIMPLEX used as a noun is rare.

 Dictionary entry details 

• HERPES SIMPLEX (noun)

Sense 1

Meaning:

An infection caused by the herpes simplex virus; affects the skin and nervous system; produces small temporary (but sometimes painful) blisters on the skin and mucous membranes

Classified under:

Nouns denoting stable states of affairs

Hypernyms ("herpes simplex" is a kind of...):

herpes (viral diseases causing eruptions of the skin or mucous membrane)

Hyponyms (each of the following is a kind of "herpes simplex"):

cold sore; fever blister; herpes labialis; oral herpes (caused by herpes simplex virus type 1 (HSV-1))

genital herpes; herpes genitalis (an infection caused by herpes simplex virus type 2 (HSV-2) that is usually transmitted by sexual contact; marked by recurrent attacks of painful eruptions on the skin and mucous membranes of the genital area)

Sense 2

Meaning:

A herpes virus that affects the skin and nervous system

Classified under:

Nouns denoting animals

Synonyms:

herpes simplex; herpes simplex virus

Hypernyms ("herpes simplex" is a kind of...):

herpes; herpes virus (any of the animal viruses that cause painful blisters on the skin)

Hyponyms (each of the following is a kind of "herpes simplex"):

herpes simplex 1; HS1; HSV-1; HSV-I (a herpes virus that causes oral herpes)

herpes simplex 2; HS2; HSV-2; HSV-II (a herpes virus that can cause genital herpes)

 Context examples 

A neuroattenuated, replication-restricted, ICP34.5 deleted (RL1 gene)-mutant herpes simplex virus (HSV) type I, constructed from wild-type strain 17, with potential oncolytic activity.

(Oncolytic HSV1716, NCI Thesaurus)

A sodium salt formulation of phosphonoacetic acid with activity against herpes simplex viruses and other members of the herpes virus family.

(Fosfonet Sodium, NCI Thesaurus)

This agent does not require phosphorylation by thymidine kinase (TK) or other kinases and therefore is active in vitro against herpes simplex virus (HSV) TK deficient mutants and cytomegalovirus (CMV) UL97 mutants.

(Foscarnet sodium, NCI Thesaurus)

Orally administered, famciclovir in vivo is converted to penciclovir triphosphate, which is active against the Herpes viruses, including herpes simplex 1 and 2 and varicella-zoster.

(Famciclovir, NCI Thesaurus)

An RGD-4C-modified, infectivity-enhanced, bicistronic type 5 adenovirus expressing herpes simplex virus thymidine kinase (HSV-tk) gene, a therapeutic suicide gene, and the somatostatin receptor type 2 (SSTR2) gene with potential antineoplastic activity.

(Ad5.SSTR/TK.RGD, NCI Thesaurus)

In gene therapy, ganciclovir is used with an altered herpes simplex virus-1 gene to kill advanced melanoma cells and brain tumor cells.

(Ganciclovir, NCI Dictionary)

A synthetic analog of the purine nucleoside, guanosine, with potent antiviral activity against herpes simplex viruses type 1 and 2, varicella-zoster virus and other viruses of the herpesvirus family.

(Acyclovir, NCI Thesaurus)

A substance used to prevent or treat cytomegalovirus and herpes simplex infections that may occur when the body is immunosuppressed.

(Acyclovir, NCI Dictionary)

Causes include infections (most commonly herpes simplex virus), drugs (e.g., sulfonamides, anticonvulsants, and antibiotics), malignancies, and collagen vascular disorders.

(Erythema Multiforme, NCI Thesaurus)

Docosanol is used topically in the treatment of recurrent herpes simplex labialis episodes and relieves associated pain and may help heal sores faster.

(Docosanol, NCI Thesaurus)