HEMOGLOBINURIA

Pronunciation (US):

(GB):

 Dictionary entry overview: What does hemoglobinuria mean? 

• HEMOGLOBINURIA (noun)
  The noun HEMOGLOBINURIA has 1 sense:

1. presence of hemoglobin in the urine

  Familiarity information: HEMOGLOBINURIA used as a noun is very rare.

 Dictionary entry details 

• HEMOGLOBINURIA (noun)

Sense 1

Meaning:

Presence of hemoglobin in the urine

Classified under:

Nouns denoting stable states of affairs

Synonyms:

haemoglobinuria; hemoglobinuria

Hypernyms ("hemoglobinuria" is a kind of...):

symptom ((medicine) any sensation or change in bodily function that is experienced by a patient and is associated with a particular disease)

 Context examples 

Includes hereditary erythrocyte membrane defects, enzyme deficiencies, hemoglobin abnormalities, stem cell defects (paroxysmal nocturnal hemoglobinuria), and alloimmune (Rh) disease of newborn.

(Hereditary Hemolytic Anemia, NIH CRISP Thesaurus)

Mutation of the gene is associated with paroxysmal nocturnal hemoglobinuria.

(PIGA wt Allele, NCI Thesaurus)

Defects of GPI anchor biosynthesis genes result in a genetic disorder, paroxysmal nocturnal hemoglobinuria.

(Glycosylphosphatidylinositol-Anchor Biosynthesis Pathway, NCI Thesaurus/KEGG)

Eculizumab binds to terminal complement protein C5, thereby blocking C5 cleavage into pro-inflammatory components and blocking the complement-mediated destruction of paroxysmal nocturnal hemoglobinuria (PNH) red blood cells.

(Eculizumab, NCI Thesaurus)

A monoclonal antibody used to prevent red blood cells from being destroyed in patients with paroxysmal nocturnal hemoglobinuria (PNH), a red blood cell disorder.

(Eculizumab, NCI Dictionary)

This suppresses excessive complement activity and may result in an inhibition of ACP-mediated hemolysis of paroxysmal nocturnal hemoglobinuria (PNH) red blood cells (RBCs) as well as preventing ACP-induced tissue damage.

(CR2-fH Fusion Protein TT30, NCI Thesaurus)